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TDG Antikörper

TDG Reaktivität: Human, Maus, Ratte IF Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN7256880
  • Target Alle TDG Antikörper anzeigen
    TDG (Thymine-DNA Glycosylase (TDG))
    Reaktivität
    • 46
    • 19
    • 11
    • 2
    • 1
    Human, Maus, Ratte
    Wirt
    • 37
    • 10
    Kaninchen
    Klonalität
    • 40
    • 8
    Polyklonal
    Konjugat
    • 41
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser TDG Antikörper ist unkonjugiert
    Applikation
    • 38
    • 11
    • 10
    • 8
    • 4
    • 4
    • 4
    • 3
    • 3
    • 2
    • 1
    Immunofluorescence (IF)
    Produktmerkmale
    Polyclonal Antibody
    Aufreinigung
    Affinity purification
    Immunogen
    Recombinant fusion protein of human TDG (NP_003202.3).
    Isotyp
    IgG
    Top Product
    Discover our top product TDG Primärantikörper
  • Applikationshinweise
    IF 1:50-1:200
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1 mg/mL
    Buffer
    PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Store at -20°C. Avoid freeze / thaw cycles.
  • Target
    TDG (Thymine-DNA Glycosylase (TDG))
    Andere Bezeichnung
    TDG (TDG Produkte)
    Synonyme
    5-MCDG antikoerper, wu:fb44b11 antikoerper, zgc:110622 antikoerper, MGC82456 antikoerper, MGC89441 antikoerper, E130317C12Rik antikoerper, JZA-3 antikoerper, Jza1 antikoerper, hTDG antikoerper, thymine DNA glycosylase antikoerper, thymine DNA glycosylase, tandem duplicate 1 antikoerper, putative g/t mismatch-specific thymine DNA glycosylase antikoerper, G/T mismatch-specific thymine DNA glycosylase antikoerper, thymine DNA glycosylase S homeolog antikoerper, thymine-DNA glycosylase antikoerper, TDG antikoerper, tdg.1 antikoerper, Smp_149220 antikoerper, Tsp_05734 antikoerper, tdg.S antikoerper, tdg antikoerper, Tdg antikoerper
    Hintergrund
    The protein encoded by this gene belongs to the TDG/mug DNA glycosylase family. Thymine-DNA glycosylase (TDG) removes thymine moieties from G/T mismatches by hydrolyzing the carbon-nitrogen bond between the sugar-phosphate backbone of DNA and the mispaired thymine. With lower activity, this enzyme also removes thymine from C/T and T/T mispairings. TDG can also remove uracil and 5-bromouracil from mispairings with guanine. This enzyme plays a central role in cellular defense against genetic mutation caused by the spontaneous deamination of 5-methylcytosine and cytosine. This gene may have a pseudogene in the p arm of chromosome 12.
    Gen-ID
    6996
    UniProt
    Q13569
    Pathways
    DNA Reparatur, Chromatin Binding
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