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TDG Antikörper

TDG Reaktivität: Maus WB Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN6972851
  • Target Alle TDG Antikörper anzeigen
    TDG (Thymine-DNA Glycosylase (TDG))
    Reaktivität
    • 47
    • 19
    • 12
    • 2
    • 1
    Maus
    Wirt
    • 37
    • 10
    Kaninchen
    Klonalität
    • 40
    • 8
    Polyklonal
    Konjugat
    • 41
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser TDG Antikörper ist unkonjugiert
    Applikation
    • 37
    • 11
    • 11
    • 8
    • 4
    • 4
    • 4
    • 3
    • 3
    • 2
    • 1
    Western Blotting (WB)
    Produktmerkmale
    In the DNA of higher eukaryotes, hydrolytic deamination of 5-methylcytosine to thymine leads to the formation of G/T mismatches. In addition, TET proteins oxidize 5- methylcytosine (5mC) to 5-hydroxymethylcytosine (5hmC), 5- formylcytosine (5fC), and 5-carboxylcytosine (5caC). TDG / Thymine-DNA glycosylase functions to correct G/T mispairs to G/C pairs and plays a role in active DNA demethylation by recognizing 5fC and 5caC and converting these to cystosine through the base excision repair (BER) pathway. TDG / Thymine-DNA glycosylase antibody (pAb) was raised in a Rabbit host. It has been validated for use in Western blot, it has been shown to react with Mouse samples.
    Aufreinigung
    Protein A Chromatography
    Immunogen
    This antibody was raised against a full-length recombinant protein corresponding to mouse thymine DNA glycosylase (TDG).
    Isotyp
    IgG
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  • Applikationshinweise
    Optimal working dilution should be determined by the investigator.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Buffer
    Purified IgG in PBS with 30 % glycerol and 0.035 % sodium azide.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Avoid repeated freeze/thaw cycles by aliquoting items into single-use fractions for storage at -20°C for up to 2 years. Keep all reagents on ice when not in storage.
  • Target
    TDG (Thymine-DNA Glycosylase (TDG))
    Andere Bezeichnung
    TDG / Thymine-DNA glycosylase (TDG Produkte)
    Synonyme
    5-MCDG antikoerper, wu:fb44b11 antikoerper, zgc:110622 antikoerper, MGC82456 antikoerper, MGC89441 antikoerper, E130317C12Rik antikoerper, JZA-3 antikoerper, Jza1 antikoerper, hTDG antikoerper, thymine DNA glycosylase antikoerper, thymine DNA glycosylase, tandem duplicate 1 antikoerper, putative g/t mismatch-specific thymine DNA glycosylase antikoerper, G/T mismatch-specific thymine DNA glycosylase antikoerper, thymine DNA glycosylase S homeolog antikoerper, thymine-DNA glycosylase antikoerper, TDG antikoerper, tdg.1 antikoerper, Smp_149220 antikoerper, Tsp_05734 antikoerper, tdg.S antikoerper, tdg antikoerper, Tdg antikoerper
    Molekulargewicht
    55 kDa
    NCBI Accession
    NP_766140
    Pathways
    DNA Reparatur, Chromatin Binding
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