MSH6 Antikörper
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- Target Alle MSH6 Antikörper anzeigen
- MSH6 (MutS Homolog 6 (E. Coli) (MSH6))
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Reaktivität
- Human, Maus, Affe
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser MSH6 Antikörper ist unkonjugiert
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Applikation
- Immunohistochemistry (IHC), Immunofluorescence (IF)
- Produktmerkmale
- Polyclonal Antibody
- Aufreinigung
- Affinity purification
- Immunogen
- Recombinant fusion protein of human MSH6 (NP_000170.1).
- Isotyp
- IgG
- Top Product
- Discover our top product MSH6 Primärantikörper
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- Applikationshinweise
- IHC 1:50-1:200 IF 1:20-1:100
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- 1 mg/mL
- Buffer
- PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- Store at -20°C. Avoid freeze / thaw cycles.
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- Target
- MSH6 (MutS Homolog 6 (E. Coli) (MSH6))
- Andere Bezeichnung
- MSH6 (MSH6 Produkte)
- Hintergrund
- This gene encodes a member of the DNA mismatch repair MutS family. In E. coli, the MutS protein helps in the recognition of mismatched nucleotides prior to their repair. A highly conserved region of approximately 150 aa, called the Walker-A adenine nucleotide binding motif, exists in MutS homologs. The encoded protein heterodimerizes with MSH2 to form a mismatch recognition complex that functions as a bidirectional molecular switch that exchanges ADP and ATP as DNA mismatches are bound and dissociated. Mutations in this gene may be associated with hereditary nonpolyposis colon cancer, colorectal cancer, and endometrial cancer. Transcripts variants encoding different isoforms have been described.
- Gen-ID
- 2956
- UniProt
- P52701
- Pathways
- DNA Reparatur, Chromatin Binding, Production of Molecular Mediator of Immune Response
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