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RECQL2 Antikörper

Dieses Anti-RECQL2-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von RECQL2 in ELISA und IHC. Geeignet für Human.
Produktnummer ABIN7254655

Kurzübersicht für RECQL2 Antikörper (ABIN7254655)

Target

Alle RECQL2 (WRN) Antikörper anzeigen
RECQL2 (WRN) (Werner syndrome RecQ like helicase (WRN))

Reaktivität

  • 39
  • 2
  • 1
Human

Wirt

  • 32
  • 10
Kaninchen

Klonalität

  • 31
  • 11
Polyklonal

Konjugat

  • 28
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Dieser RECQL2 Antikörper ist unkonjugiert

Applikation

  • 33
  • 17
  • 11
  • 9
  • 6
  • 4
  • 4
  • 3
  • 1
  • 1
ELISA, Immunohistochemistry (IHC)
  • Produktmerkmale

    Polyclonal Antibody

    Aufreinigung

    Antigen affinity purification

    Immunogen

    Synthetic peptide of human WRN

    Isotyp

    IgG
  • Applikationshinweise

    IHC 1:30-1:150, ELISA 1:5000-1:10000

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Liquid

    Konzentration

    0.8 mg/mL

    Buffer

    PBS with 0.05 % Sodium azide and 40 % Glycerol, pH 7.4

    Konservierungsmittel

    Sodium azide

    Vorsichtsmaßnahmen

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Lagerung

    -20 °C

    Informationen zur Lagerung

    Store at -20°C. Avoid freeze / thaw cycles.
  • Target

    RECQL2 (WRN) (Werner syndrome RecQ like helicase (WRN))

    Andere Bezeichnung

    WRN

    Hintergrund

    This gene encodes a member of the RecQ subfamily and the DEAH (Asp-Glu-Ala-His) subfamily of DNA and RNA helicases. DNA helicases are involved in many aspects of DNA metabolism, including transcription, replication, recombination, and repair. This protein contains a nuclear localization signal in the C-terminus and shows a predominant nucleolar localization. It possesses an intrinsic 3' to 5' DNA helicase activity, and is also a 3' to 5' exonuclease. Based on interactions between this protein and Ku70/80 heterodimer in DNA end processing, this protein may be involved in the repair of double strand DNA breaks. Defects in this gene are the cause of Werner syndrome, an autosomal recessive disorder characterized by premature aging.

    UniProt

    Q14191

    Pathways

    DNA Reparatur
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