RECQL2 Antikörper

Produktnummer ABIN2668372

Es gibt 1 Publikation für dieses Produkt. Der Maus Monoklonal anti-RECQL2 Antikörper wird verwendet zum Nachweis von RECQL2 in Proben von Human. Er wurde validiert für WB, IHC, IF und ICC.

Kurzübersicht für RECQL2 Antikörper (ABIN2668372)

Target: RECQL2 (WRN) (Werner syndrome RecQ like helicase (WRN))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser RECQL2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC)

Klon: 195C

Produktdetails anti-RECQL2 Antikörper

Verwendungszweck: WRN antibody (mAb) (Clone 195C)

Aufreinigung: Protein G Chromatography

Immunogen: This WRN antibody was raised against a recombinant protein corresponding to amino acids 1072 - 1432 of human WRN.

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: ICC/IF: 0.5 μg/mL dilution IHC(P): User optimization required WB: 0.5 - 2 μg/mL dilution

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1 μg/μL

Buffer: Purified IgG in PBS with 30 % glycerol and 0.035 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze/thaw cycles by aliquoting items into single-use fractions,Keep all reagents on ice when not in storage

Lagerung: -20 °C

Informationen zur Lagerung: Some products may be shipped at room temperature. This will not affect their stability or performance. Avoid repeated freeze/thaw cycles by aliquoting items into single-use fractions for storage at -20°C for up to 2 years. Keep all reagents on ice when not in storage.

Haltbarkeit: 24 months

Referenzen für anti-RECQL2 Antikörper (ABIN2668372)

Opresko, Calvo, von Kobbe: "Role for the Werner syndrome protein in the promotion of tumor cell growth." in: Mechanisms of ageing and development, Vol. 128, Issue 7-8, pp. 423-36, (2007) (PubMed).

Details zu RECQL2

Target: RECQL2 (WRN) (Werner syndrome RecQ like helicase (WRN))

Andere Bezeichnung: WRN

Hintergrund: WRN protein is a RECQ helicase that contains 3' to 5' helicase activity and DNA-dependent ATPase activity. WRN takes part in many processes, including DNA replication, recombination, repair, and telomere maintenance. Mutations in the gene encoding WRN cause an autosomal recessive segmental progeria called Werner syndrome (WS). WS patients prematurely develop atrophic skin, thin gray hair, osteoporosis, type II diabetes, cataracts, arteriosclerosis and cancer.

Molekulargewicht: 162 kDa

Gen-ID: 7486

NCBI Accession: NP_000544

Pathways: DNA Reparatur