Caspase 1 Antikörper (Cleaved-Asp210)
Kurzübersicht für Caspase 1 Antikörper (Cleaved-Asp210) (ABIN7251010)
Target
Alle Caspase 1 (CASP1) Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- Cleaved-Asp210
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Produktmerkmale
- Polyclonal Antibody
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Aufreinigung
- Affinity purification
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Immunogen
- Synthesized peptide derived from the Internal region of human Caspase-1
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Isotyp
- IgG
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Applikationshinweise
- WB 1:500-2000, IHC 1:50-300, IF 1:50-300
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- 1 mg/mL
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Buffer
- PBS with 0.02 % sodium azide, 0.5 % BSA and 50 % glycerol, pH 7.4
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- Store at -20°C. Avoid freeze / thaw cycles.
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- Caspase 1 (CASP1)
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Andere Bezeichnung
- CASP1
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Hintergrund
- Thiol protease that cleaves IL-1 beta between an Asp and an Ala, releasing the mature cytokine which is involved in a variety of inflammatory processes. Important for defense against pathogens. Cleaves and activates sterol regulatory element binding proteins (SREBPs). Can also promote apoptosis.
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Molekulargewicht
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Observed_MW: 25 kDa
Calculated_MW: 45 kDa
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UniProt
- P29466
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Pathways
- Apoptose, Interferon-gamma Pathway, Positive Regulation of Endopeptidase Activity, Inflammasome
Target
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