CDC25A Antikörper
Kurzübersicht für CDC25A Antikörper (ABIN7249588)
Target
Alle CDC25A Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Produktmerkmale
- Polyclonal Antibody
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Aufreinigung
- Affinity purification
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Immunogen
- KLH conjugated Synthetic peptide corresponding to Mouse Cdc25A
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Isotyp
- IgG
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Applikationshinweise
- WB 1:500-1:1000, IHC 1:500-1:1000
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- 0.96 mg/mL
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Buffer
- PBS with 0.02 % sodium azide, 1 % BSA and 50 % glycerol, pH 7.4
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- Store at -20°C. Avoid freeze / thaw cycles.
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- CDC25A (Cell Division Cycle 25 Homolog A (S. Pombe) (CDC25A))
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Andere Bezeichnung
- CDC25A
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Hintergrund
- CDC25A is a member of the CDC25 family of phosphatases. CDC25A is required for progression from G1 to the S phase of the cell cycle. It activates the cyclin-dependent kinase CDC2 by removing two phosphate groups. CDC25A is specifically degraded in response to DNA damage, which prevents cells with chromosomal abnormalities from progressing through cell division. CDC25A is an oncogene, although its exact role in oncogenesis has not been demonstrated. Two transcript variants encoding different isoforms have been found for this gene.
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Molekulargewicht
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Observed_MW: 70 kDa
Calculated_MW: 65-70 kDa
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UniProt
- P30304, P48965, P48964
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Pathways
- Zellzyklus, Mitotic G1-G1/S Phases, M Phase
Target
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