Der Kaninchen Polyklonal Anti-VAMP2-Antikörper wurde für IHC und ELISA validiert. Er ist geeignet, VAMP2 in Proben von Human, Maus und Ratte zu detektieren.
VAMP2
Reaktivität: Human
WB, ELISA
Wirt: Maus
Monoclonal
3E5
unconjugated
Applikationshinweise
IHC 1:25-100, ELISA 1:2000-5000
Beschränkungen
Nur für Forschungszwecke einsetzbar
Format
Liquid
Konzentration
0.3 mg/mL
Buffer
PBS with 0.05 % sodium azide and 50 % glycerol, PH7.4
Konservierungsmittel
Sodium azide
Vorsichtsmaßnahmen
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung
-20 °C
Informationen zur Lagerung
Store at -20°C. Avoid freeze / thaw cycles.
Target
VAMP2
(Vesicle-Associated Membrane Protein 2 (Synaptobrevin 2) (VAMP2))
Andere Bezeichnung
VAMP2
Hintergrund
The protein encoded by this gene is a member of the vesicle-associated membrane protein (VAMP)/synaptobrevin family. Synaptobrevins/VAMPs, syntaxins, and the 25-kD synaptosomal-associated protein SNAP25 are the main components of a protein complex involved in the docking and/or fusion of synaptic vesicles with the presynaptic membrane. This gene is thought to participate in neurotransmitter release at a step between docking and fusion. The protein forms a stable complex with syntaxin, synaptosomal-associated protein, 25 kD, and synaptotagmin. It also forms a distinct complex with synaptophysin. It is a likely candidate gene for familial infantile myasthenia (FIMG) because of its map location and because it encodes a synaptic vesicle protein of the type that has been implicated in the pathogenesis of FIMG.