CDC25B Antikörper
Kurzübersicht für CDC25B Antikörper (ABIN7238204)
Target
Alle CDC25B Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Produktmerkmale
- Polyclonal Antibody
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Aufreinigung
- Affinity purification
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Immunogen
- Synthetic peptide of human CDC25B
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Isotyp
- IgG
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Applikationshinweise
- IHC 1:50-1:200
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- 0.2 mg/mL
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Buffer
- PBS with 0.05 % sodium azide and 50 % glycerol, PH7.4
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- Store at -20°C. Avoid freeze / thaw cycles.
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- CDC25B (Cell Division Cycle 25 Homolog B (S. Pombe) (CDC25B))
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Andere Bezeichnung
- CDC25B
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Hintergrund
- CDC25B is a member of the CDC25 family of phosphatases. CDC25B activates the cyclin dependent kinase CDC2 by removing two phosphate groups and it is required for entry into mitosis. CDC25B shuttles between the nucleus and the cytoplasm due to nuclear localization and nuclear export signals. The protein is nuclear in the M and G1 phases of the cell cycle and moves to the cytoplasm during S and G2. CDC25B has oncogenic properties, although its role in tumor formation has not been determined. Multiple transcript variants for this gene exist.
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NCBI Accession
- NP_004349
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UniProt
- P30305
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Pathways
- Zellzyklus, M Phase, Autophagie
Target
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