Retinoblastoma Binding Protein 8 Antikörper
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- Target Alle Retinoblastoma Binding Protein 8 (RBBP8) Antikörper anzeigen
- Retinoblastoma Binding Protein 8 (RBBP8)
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Reaktivität
- Human, Maus, Ratte
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser Retinoblastoma Binding Protein 8 Antikörper ist unkonjugiert
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Applikation
- ELISA, Immunohistochemistry (IHC)
- Produktmerkmale
- Polyclonal Antibody
- Aufreinigung
- Affinity purification
- Immunogen
- Recombinant protein of human RBBP8
- Isotyp
- IgG
- Top Product
- Discover our top product RBBP8 Primärantikörper
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- Applikationshinweise
- IHC 1:100-1:300
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- 0.7 mg/mL
- Buffer
- PBS with 0.05 % sodium azide and 50 % glycerol, PH7.4
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- Store at -20°C. Avoid freeze / thaw cycles.
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- Target
- Retinoblastoma Binding Protein 8 (RBBP8)
- Andere Bezeichnung
- RBBP8 (RBBP8 Produkte)
- Hintergrund
- The protein encoded by this gene is a ubiquitously expressed nuclear protein. It is found among several proteins that bind directly to retinoblastoma protein, which regulates cell proliferation. This protein complexes with transcriptional co-repressor CTBP. It is also associated with BRCA1 and is thought to modulate the functions of BRCA1 in transcriptional regulation, DNA repair, and/or cell cycle checkpoint control. It is suggested that this gene may itself be a tumor suppressor acting in the same pathway as BRCA1. Three transcript variants encoding two different isoforms have been found for this gene. More transcript variants exist, but their full-length natures have not been determined.
- UniProt
- Q99708
- Pathways
- Zellzyklus, DNA Reparatur
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