MAP1LC3A Antikörper (N-Term)

Produktnummer ABIN6991931

Der Kaninchen Polyklonal anti-MAP1LC3A Antikörper wird verwendet zum Nachweis von MAP1LC3A in Proben von Human. Er wurde validiert für WB, ELISA, IF und IHC (p).

Kurzübersicht für MAP1LC3A Antikörper (N-Term) (ABIN6991931)

Target: MAP1LC3A (Microtubule-Associated Protein 1 Light Chain 3 alpha (MAP1LC3A))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser MAP1LC3A Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Produktdetails anti-MAP1LC3A Antikörper

Bindungsspezifität: N-Term

Spezifität: MAP1LC3A antibody is human specific. At least two isoforms of MAP1LC3A are known to exist. MAP1LC3A antibody is predicted to not cross-react with MAP1LC3B or MAP1LC3C.

Aufreinigung: MAP1LC3A antibody is affinity chromatography purified via peptide column.

Immunogen: MAP1LC3A antibody was raised against a 10 amino acid peptide near the amino terminus of human MAP1LC3A. The immunogen is located within the first 50 amino acids of MAP1LC3A.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: MAP1LC3A antibody can be used for detection of MAP1LC3A by Western blot at 1 - 2 μ,g/mL. Antibody can also be used for Immunohistochemistry starting at 5 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.

Antibody validated: Western Blot in human samples, Immunohistochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: MAP1LC3A antibody is supplied in PBS containing 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,4 °C

Informationen zur Lagerung: MAP1LC3A antibody can be stored at 4°C for three months and -20°C, stable for up to one year.

Details zu MAP1LC3A

Target: MAP1LC3A (Microtubule-Associated Protein 1 Light Chain 3 alpha (MAP1LC3A))

Andere Bezeichnung: MAP1LC3A

Hintergrund: Microtubule-associated proteins (MAPs) regulate microtubule stability and play critical roles in neuronal development and plasticity (1). MAP1LC3A belongs to the MAP1 LC3 family of proteins that form mature complexes with MAP1A and MAP1B which are thought to be important in the formation and development of axons and dendrites (2). MAP1LC3A is one of three isoforms of MAP1LC3, the mammalian homolog of yeast ATG8, an essential autophagy protein. These isoforms exhibit distinct expression patterns and MAP1LC3A, like MAP1LC3A but not MAP1LC3B, is post-translationally modified, suggesting the three isoforms may have different physiological functions (3).

Molekulargewicht: Predicted: 14 kDa

Observed: 17 kDa

Gen-ID: 84557

NCBI Accession: NP_852610

UniProt: Q9H492

Pathways: Autophagie