BCL3 Antikörper (C-Term)

Produktnummer ABIN6991805

Der Kaninchen Polyklonal Anti-BCL3-Antikörper wurde für WB und ELISA validiert. Er ist geeignet, BCL3 in Proben von Human zu detektieren.

Kurzübersicht für BCL3 Antikörper (C-Term) (ABIN6991805)

Target: BCL3 (B-Cell CLL/lymphoma 3 (BCL3))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser BCL3 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Produktdetails anti-BCL3 Antikörper

Bindungsspezifität: AA 360-410, C-Term

Aufreinigung: BCL3 Antibody is affinity chromatography purified via peptide column.

Immunogen: Rabbit polyclonal BCL3 antibody was raised against a 17 amino acid peptide near the carboxy terminus of human BCL3. The immunogen is located within amino acids 360 - 410 of BCL3.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: BCL3 antibody can be used for detection of BCL3 by Western blot at 1 - 2 μ,g/mL.

Antibody validated: Western Blot in human samples. All other applications and species not yet tested.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: BCL3 Antibody is supplied in PBS containing 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,4 °C

Informationen zur Lagerung: BCL3 antibody can be stored at 4°C for three months and -20°C, stable for up to one year.

Details zu BCL3

Target: BCL3 (B-Cell CLL/lymphoma 3 (BCL3))

Andere Bezeichnung: BCL3

Hintergrund: BCL3 Antibody: The proto-oncogene Bcl-3, believed to be involved in certain human B cell leukemias, encodes a protein that contributes to the regulation of transcriptional activation of NF-κ,-B target genes. BCL3 contains seven ankyrin repeats, which are most closely related to those found in I-κ,-B proteins. The expression of this gene can be induced by NF-κ,-B, which forms a part of the autoregulatory loop that controls the nuclear residence of p50 NF-κ,-B. It contributes to the regulation of cell proliferation. A chromosomal aberration involving BCL3 may be a cause of B-cell chronic lymphocytic leukemia.

Molekulargewicht: Predicted: 50 kDa

Gen-ID: 602

NCBI Accession: NP_005169

UniProt: P20749

Pathways: NF-kappaB Signalweg, Maintenance of Protein Location, Protein targeting to Nucleus