ATG14 Antikörper (AA 270-320)

Produktnummer ABIN6991757

Der Kaninchen Polyklonal Anti-ATG14-Antikörper wurde für WB, ELISA und IF validiert. Er ist geeignet, ATG14 in Proben von Human, Maus und Ratte zu detektieren.

Kurzübersicht für ATG14 Antikörper (AA 270-320) (ABIN6991757)

Target: ATG14 (ATG14 Autophagy Related 14 (ATG14))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ATG14 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunofluorescence (IF)

Produktdetails anti-ATG14 Antikörper

Bindungsspezifität: AA 270-320

Spezifität: At least three isoforms of ATG14 are known to exist, this antibody will detect all three isoforms

Aufreinigung: ATG14 Antibody is affinity chromatography purified via peptide column.

Immunogen: ATG14 antibody was raised against an 18 amino acid synthetic peptide near the center of human ATG14. The immunogen is located within amino acids 270 - 320 of ATG14.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: ATG14 antibody can be used for detection of ATG14 by Western blot at 1 - 2 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.

Antibody validated: Western Blot in human samples and Immunofluorescence in human samples. All other applications and species not yet tested.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: ATG14 Antibody is supplied in PBS containing 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,4 °C

Informationen zur Lagerung: ATG14 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Details zu ATG14

Target: ATG14 (ATG14 Autophagy Related 14 (ATG14))

Andere Bezeichnung: ATG14

Hintergrund: ATG14 Antibody: Autophagy, the process of bulk degradation of cellular proteins through an autophagosomic-lysosomal pathway is important for normal growth control and may be defective in tumor cells. It is involved in the preservation of cellular nutrients under starvation conditions as well as the normal turnover of cytosolic components. This process is negatively regulated by TOR (Target of rapamycin) through phosphorylation of autophagy protein ATG1. ATG14 is a subunit of a class III phosphatidylinositol (PtdIns) 3-kinase complex that targets the complex to the endoplasmic reticulum, the site of autophagosome formation.

Molekulargewicht: 54 kDa

Gen-ID: 22863

NCBI Accession: NP_055739

UniProt: Q6ZNE5

Pathways: Autophagie