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IRAK1 Antikörper (AA 618-712)
IRAK1
Reaktivität: Human, Maus
WB, ELISA, IHC (p)
Wirt: Maus
Monoclonal
8F1A7
unconjugated
Produktnummer ABIN6990202
Produktdetails anti-IRAK1 Antikörper
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Target
Alle IRAK1 Antikörper anzeigen
IRAK1
(Interleukin-1 Receptor-Associated Kinase 1 (IRAK1))
Bindungsspezifität
Alle Epitope für IRAK1 Antikörper
AA 618-712
Reaktivität
Alle Reaktivitäten für IRAK1 Antikörper
Human, Maus
Wirt
Alle Wirte für IRAK1 Antikörper
Maus
Klonalität
Alle Klonalitäten für IRAK1 Antikörper
Monoklonal
Konjugat
Alle Konjugate für IRAK1 Antikörper
Dieser IRAK1 Antikörper ist unkonjugiert
Applikation
Alle Applikationen für IRAK1 Antikörper
Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
Aufreinigung
IRAK Monoclonal Antibody is Protein G purified.
Immunogen
Recombinant protein corresponding to amino acids 618 - 712 of human IRAK.
Klon
8F1A7
Isotyp
IgG1
Top Product
Discover our top product IRAK1 Primärantikörper
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Anwendungsinformationen
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Applikationshinweise
IRAK antibody can be used for Western blot at 1 - 2 μ,g/mL. Antibody can also be used for immunohistochemistry starting at 5 μ,g/mL. Antibody validated: Western Blot in mouse samples and Immunohistochemistry in rat samples. All other applications and species not yet tested.
Beschränkungen
Nur für Forschungszwecke einsetzbar
Handhabung
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Format
Liquid
Konzentration
1 mg/mL
Buffer
IRAK Monoclonal Antibody is supplied in PBS containing 0.02 % sodium azide.
Konservierungsmittel
Sodium azide
Vorsichtsmaßnahmen
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung
-20 °C
Informationen zur Lagerung
IRAK monoclonal antibody can be stored at -20°C, stable for one year.
Details zu IRAK1
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Target
IRAK1
(Interleukin-1 Receptor-Associated Kinase 1 (IRAK1))
Andere Bezeichnung
IRAK (IRAK1 Produkte )
Synonyme
IRAK1 antikoerper, IRAK antikoerper, pelle antikoerper, AA408924 antikoerper, IRAK-1 antikoerper, IRAK1-S antikoerper, Il1rak antikoerper, Plpk antikoerper, mPLK antikoerper, RGD1563841 antikoerper, interleukin 1 receptor associated kinase 1 antikoerper, interleukin-1 receptor-associated kinase 1 antikoerper, IRAK1 antikoerper, irak1 antikoerper, Irak1 antikoerper
Hintergrund
IRAK Monoclonal Antibody: Nuclear factor kappa B (NF-kappaB) is a ubiquitous transcription factor and an essential mediator of gene expression during activation of immune and inflammatory responses. NF-κ,B mediates the expression of a great variety of genes in response to extracellular stimuli including IL-1, TNFalpha and LPS. A serine/threonine protein kinase associated with IL-1 receptor (IRAK) and its homologue mouse pelle-like protein kinase (mPLK) were identified recently. IRAK is associated with the IL-1 receptor subunits IL-1RI and IL-1RAcP after IL-1 binding and serves as a signaling molecule to mediate IL-1 response. IRAK mediates a signaling cascade leading to NF-κ,B activation by members in IL-1 family including IL-1 and a novel cytokine IL-18 (also termed IGIF).
Gen-ID
3654
UniProt
P51617
Pathways
NF-kappaB Signalweg , TLR Signalweg , Neurotrophin Signalübertragung , Activation of Innate immune Response , Cellular Response to Molecule of Bacterial Origin , Toll-Like Receptors Cascades
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