ROCK1 Antikörper
Kurzübersicht für ROCK1 Antikörper (ABIN6989875)
Target
Alle ROCK1 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Kreuzreaktivität
- Human, Maus, Ratte
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Aufreinigung
- Purified by Protein A.
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Immunogen
- Recombinant fusion protein containing a sequence corresponding to amino acids 400-660 of human ROCK1 (NP_005397.1).
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Isotyp
- IgG
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anti-rho-Associated, Coiled-Coil Containing Protein Kinase 1 (ROCK1) (N-Term) antibody
KO Validated ROCK1 Reaktivität: Human WB, IP, IF, IHC (p), ICC Wirt: Kaninchen Polyclonal unconjugated
anti-rho-Associated, Coiled-Coil Containing Protein Kinase 1 (ROCK1) (AA 1001-1200) antibodyROCK1 Reaktivität: Human, Maus, Ratte WB, ELISA, IF (cc), IF (p), IHC (p), IHC (fro) Wirt: Kaninchen Polyclonal unconjugated
anti-rho-Associated, Coiled-Coil Containing Protein Kinase 1 (ROCK1) (AA 401-510) antibodyROCK1 Reaktivität: Human WB, ELISA, IF Wirt: Maus Monoclonal 2E2 unconjugated
anti-rho-Associated, Coiled-Coil Containing Protein Kinase 1 (ROCK1) (pSer456), (pThr455) antibodyROCK1 Reaktivität: Human, Maus, Ratte WB, ELISA, IF (cc), IF (p), FACS, IHC (p), IHC (fro) Wirt: Kaninchen Polyclonal unconjugated
anti-rho-Associated, Coiled-Coil Containing Protein Kinase 1 (ROCK1) (AA 400-660) antibodyROCK1 Reaktivität: Human WB, IHC, IP Wirt: Kaninchen Polyclonal unconjugated
anti-rho-Associated, Coiled-Coil Containing Protein Kinase 1 (ROCK1) antibodyROCK1 Reaktivität: Human ELISA Wirt: Maus Monoclonal 1H4 unconjugated
anti-rho-Associated, Coiled-Coil Containing Protein Kinase 1 (ROCK1) (AA 405-668) antibodyROCK1 Reaktivität: Human WB, ELISA, IHC, IF Wirt: Kaninchen Polyclonal unconjugated
anti-rho-Associated, Coiled-Coil Containing Protein Kinase 1 (ROCK1) (AA 1094-1323) antibodyROCK1 Reaktivität: Maus WB, IHC, IP, ICC Wirt: Kaninchen Polyclonal unconjugated
anti-rho-Associated, Coiled-Coil Containing Protein Kinase 1 (ROCK1) antibodyROCK1 Reaktivität: Human, Maus, Ratte WB, IHC, IP, IF, FACS, ICC Wirt: Kaninchen Monoclonal unconjugated
anti-rho-Associated, Coiled-Coil Containing Protein Kinase 1 (ROCK1) (Internal Region) antibodyROCK1 Reaktivität: Human, Maus, Ratte, Affe WB, ELISA, IHC, ICC Wirt: Kaninchen Polyclonal unconjugated
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Applikationshinweise
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WB 1:300-5000
IHC-P 1:200-400
IP(1-2 μg)
IHC() -
Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- 1 μg/μL
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Buffer
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
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Konservierungsmittel
- ProClin
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Vorsichtsmaßnahmen
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- Store at -20°C for 12 months.
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Haltbarkeit
- 12 months
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- ROCK1 (rho-Associated, Coiled-Coil Containing Protein Kinase 1 (ROCK1))
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Andere Bezeichnung
- ROCK1
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Hintergrund
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Synonyms: ROCK1,P160ROCK,ROCK-I
Background: This gene encodes a protein serine/threonine kinase that is activated when bound to the GTP-bound form of Rho. The small GTPase Rho regulates formation of focal adhesions and stress fibers of fibroblasts, as well as adhesion and aggregation of platelets and lymphocytes by shuttling between the inactive GDP-bound form and the active GTP-bound form. Rho is also essential in cytokinesis and plays a role in transcriptional activation by serum response factor. This protein, a downstream effector of Rho, phosphorylates and activates LIM kinase, which in turn, phosphorylates cofilin, inhibiting its actin-depolymerizing activity. A pseudogene, related to this gene, is also located on chromosome 18.
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Gen-ID
- 6093
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UniProt
- Q13464
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Pathways
- Microtubule Dynamics, WNT Signalweg, M Phase, Maintenance of Protein Location, Signaling Events mediated by VEGFR1 and VEGFR2, Thromboxane A2 Receptor Signaling
Target
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