ROCK1 Antikörper (AA 401-510)

Produktnummer ABIN562671

Produktdetails anti-ROCK1 Antikörper

Target: ROCK1 (rho-Associated, Coiled-Coil Containing Protein Kinase 1 (ROCK1))

Bindungsspezifität: AA 401-510

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser ROCK1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunofluorescence (IF)

Verwendungszweck: Mouse monoclonal antibody raised against a partial recombinant ROCK1.

Sequenz: SNRRYLSSAN PNDNRTSSNA DKSLQESLQK TIYKLEEQLH NEMQLKDEME QKCRTSNIKL DKIMKELDEE GNQRRNLEST VSQIEKEKML LQHRINEYQR KAEQENEKRR

Kreuzreaktivität: Human

Produktmerkmale: Antibody Reactive Against Recombinant Protein.

Immunogen: ROCK1 (NP_005397, 401 a.a. ~ 510 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

Klon: 2E2

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: In 1x PBS, pH 7.4

Handhabung: Aliquot to avoid repeated freezing and thawing.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.

Referenzen für anti-ROCK1 Antikörper (ABIN562671)

Nishimura, Bereczky, Yoshioka, Taniguchi, Itoh: "A novel role of Rho-kinase in the regulation of ligand-induced phosphorylated EGFR endocytosis via the early/late endocytic pathway in human fibrosarcoma cells." in: Journal of molecular histology, Vol. 42, Issue 5, pp. 427-42, (2011) (PubMed).

Gong, Fang, Peng, Liu, Du: "Integration of virtual screening with high-throughput screening for the identification of novel Rho-kinase I inhibitors." in: Journal of biotechnology, Vol. 145, Issue 3, pp. 295-303, (2010) (PubMed).

Details zu ROCK1

Target: ROCK1 (rho-Associated, Coiled-Coil Containing Protein Kinase 1 (ROCK1))

Andere Bezeichnung: ROCK1 (ROCK1 Produkte)

Hintergrund: Full Gene Name: Rho-associated, coiled-coil containing protein kinase 1
Synonyms: MGC131603,MGC43611,P160ROCK,PRO0435

Gen-ID: 6093

NCBI Accession: NM_005406

Pathways: Microtubule Dynamics, WNT Signalweg, M Phase, Maintenance of Protein Location, Signaling Events mediated by VEGFR1 and VEGFR2, Thromboxane A2 Receptor Signaling