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ALOX15 Antikörper (AA 600-650)

Der Kaninchen Polyklonal Anti-ALOX15-Antikörper wurde für WB, IF, IHC (p) und IHC (fro) validiert. Er ist geeignet, ALOX15 in Proben von Human zu detektieren.
Produktnummer ABIN6989093

Kurzübersicht für ALOX15 Antikörper (AA 600-650) (ABIN6989093)

Target

Alle ALOX15 Antikörper anzeigen
ALOX15 (Arachidonate 15-Lipoxygenase (ALOX15))

Reaktivität

  • 67
  • 26
  • 22
  • 2
  • 2
  • 2
  • 2
  • 1
Human

Wirt

  • 54
  • 15
  • 1
Kaninchen

Klonalität

  • 55
  • 15
Polyklonal

Konjugat

  • 35
  • 8
  • 6
  • 3
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Dieser ALOX15 Antikörper ist unkonjugiert

Applikation

  • 43
  • 26
  • 17
  • 13
  • 13
  • 13
  • 13
  • 10
  • 10
  • 8
  • 3
  • 1
  • 1
Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
  • Bindungsspezifität

    • 16
    • 12
    • 4
    • 4
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 600-650

    Kreuzreaktivität

    Human

    Aufreinigung

    Purified by Protein A.

    Immunogen

    KLH conjugated synthetic peptide derived from human ALOX15

    Isotyp

    IgG
  • Applikationshinweise

    WB 1:300-5000
    IHC-P 1:200-400
    IHC-F 1:100-500
    IF()

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Liquid

    Konzentration

    1 μg/μL

    Buffer

    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

    Konservierungsmittel

    ProClin

    Vorsichtsmaßnahmen

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

    Lagerung

    4 °C,-20 °C

    Informationen zur Lagerung

    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

    Haltbarkeit

    12 months
  • Target

    ALOX15 (Arachidonate 15-Lipoxygenase (ALOX15))

    Andere Bezeichnung

    ALOX15

    Hintergrund

    Synonyms: 15 lipoxygenase 1, 15 LIPOXYGENASE RETICULOCYTE ARACHIDONATE, 15 LOX, 15 LOX 1, 15-LOX, 15LOX 1, ALOX15, Arachidonate 15 lipoxygenase, Arachidonate 15-lipoxygenase, Arachidonate omega 6 lipoxygenase, Arachidonate omega-6 lipoxygenase, LOG15, LOX15_HUMAN.

    Background: Lipoxygenases are a family of enzymes which dioxygenate unsaturated fatty acids, thus initiating lipoperoxidation of membranes and synthesis of signaling molecules, as well as inducing structural and metabolic changes in the cell. The Lox enzymes in mammals include 12-LO and 15-LO, which are classified with respect to their positional specificity of the deoxygenation of their most common substrate, arachidonic acid. The metabolism of arachidonic acid leads to the generation of biologically active metabolites that have been implicated in cell growth and proliferation, as well as survival and apoptosis. 15-Lipoxygenase (15-LO) acts in physiological membrane remodeling and the pathogenesis of atherosclerosis, inflammation, and carcinogenesis. It is highly regulated and expressed in a tissue- and cell-type-specific fashion. IL-4 and IL-13 play important roles in transactivating the 15-LO gene. Overexpression of 15-LO type 1 in prostate cancer contributes to the cancer progression by regulating IGF-1R expression and activation.

    Gen-ID

    246

    UniProt

    P16050

    Pathways

    Regulation of Actin Filament Polymerization
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