ALOX15 Antikörper (AA 600-650)
-
- Target Alle ALOX15 Antikörper anzeigen
- ALOX15 (Arachidonate 15-Lipoxygenase (ALOX15))
-
Bindungsspezifität
- AA 600-650
-
Reaktivität
- Human
-
Wirt
- Kaninchen
-
Klonalität
- Polyklonal
-
Konjugat
- Dieser ALOX15 Antikörper ist unkonjugiert
-
Applikation
- Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
- Kreuzreaktivität
- Human
- Aufreinigung
- Purified by Protein A.
- Immunogen
- KLH conjugated synthetic peptide derived from human ALOX15
- Isotyp
- IgG
- Top Product
- Discover our top product ALOX15 Primärantikörper
-
-
- Applikationshinweise
-
WB 1:300-5000
IHC-P 1:200-400
IHC-F 1:100-500
IF() - Beschränkungen
- Nur für Forschungszwecke einsetzbar
-
- Format
- Liquid
- Konzentration
- 1 μg/μL
- Buffer
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
- Konservierungsmittel
- ProClin
- Vorsichtsmaßnahmen
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- Lagerung
- 4 °C,-20 °C
- Informationen zur Lagerung
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
- Haltbarkeit
- 12 months
-
- Target
- ALOX15 (Arachidonate 15-Lipoxygenase (ALOX15))
- Andere Bezeichnung
- ALOX15 (ALOX15 Produkte)
- Hintergrund
-
Synonyms: 15 lipoxygenase 1, 15 LIPOXYGENASE RETICULOCYTE ARACHIDONATE, 15 LOX, 15 LOX 1, 15-LOX, 15LOX 1, ALOX15, Arachidonate 15 lipoxygenase, Arachidonate 15-lipoxygenase, Arachidonate omega 6 lipoxygenase, Arachidonate omega-6 lipoxygenase, LOG15, LOX15_HUMAN.
Background: Lipoxygenases are a family of enzymes which dioxygenate unsaturated fatty acids, thus initiating lipoperoxidation of membranes and synthesis of signaling molecules, as well as inducing structural and metabolic changes in the cell. The Lox enzymes in mammals include 12-LO and 15-LO, which are classified with respect to their positional specificity of the deoxygenation of their most common substrate, arachidonic acid. The metabolism of arachidonic acid leads to the generation of biologically active metabolites that have been implicated in cell growth and proliferation, as well as survival and apoptosis. 15-Lipoxygenase (15-LO) acts in physiological membrane remodeling and the pathogenesis of atherosclerosis, inflammation, and carcinogenesis. It is highly regulated and expressed in a tissue- and cell-type-specific fashion. IL-4 and IL-13 play important roles in transactivating the 15-LO gene. Overexpression of 15-LO type 1 in prostate cancer contributes to the cancer progression by regulating IGF-1R expression and activation.
- Gen-ID
- 246
- UniProt
- P16050
- Pathways
- Regulation of Actin Filament Polymerization
-