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ALOX15 Antikörper (AA 600-650)

ALOX15 Reaktivität: Human WB, IF, IHC (p), IHC (fro) Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN6989093
  • Target Alle ALOX15 Antikörper anzeigen
    ALOX15 (Arachidonate 15-Lipoxygenase (ALOX15))
    Bindungsspezifität
    • 16
    • 12
    • 4
    • 4
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 600-650
    Reaktivität
    • 67
    • 26
    • 22
    • 2
    • 2
    • 2
    • 2
    • 1
    Human
    Wirt
    • 54
    • 15
    • 1
    Kaninchen
    Klonalität
    • 55
    • 15
    Polyklonal
    Konjugat
    • 35
    • 8
    • 6
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser ALOX15 Antikörper ist unkonjugiert
    Applikation
    • 43
    • 26
    • 17
    • 13
    • 13
    • 13
    • 13
    • 10
    • 10
    • 8
    • 3
    • 1
    • 1
    Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
    Kreuzreaktivität
    Human
    Aufreinigung
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic peptide derived from human ALOX15
    Isotyp
    IgG
    Top Product
    Discover our top product ALOX15 Primärantikörper
  • Applikationshinweise
    WB 1:300-5000
    IHC-P 1:200-400
    IHC-F 1:100-500
    IF()
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1 μg/μL
    Buffer
    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
    Konservierungsmittel
    ProClin
    Vorsichtsmaßnahmen
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Lagerung
    4 °C,-20 °C
    Informationen zur Lagerung
    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
    Haltbarkeit
    12 months
  • Target
    ALOX15 (Arachidonate 15-Lipoxygenase (ALOX15))
    Andere Bezeichnung
    ALOX15 (ALOX15 Produkte)
    Hintergrund

    Synonyms: 15 lipoxygenase 1, 15 LIPOXYGENASE RETICULOCYTE ARACHIDONATE, 15 LOX, 15 LOX 1, 15-LOX, 15LOX 1, ALOX15, Arachidonate 15 lipoxygenase, Arachidonate 15-lipoxygenase, Arachidonate omega 6 lipoxygenase, Arachidonate omega-6 lipoxygenase, LOG15, LOX15_HUMAN.

    Background: Lipoxygenases are a family of enzymes which dioxygenate unsaturated fatty acids, thus initiating lipoperoxidation of membranes and synthesis of signaling molecules, as well as inducing structural and metabolic changes in the cell. The Lox enzymes in mammals include 12-LO and 15-LO, which are classified with respect to their positional specificity of the deoxygenation of their most common substrate, arachidonic acid. The metabolism of arachidonic acid leads to the generation of biologically active metabolites that have been implicated in cell growth and proliferation, as well as survival and apoptosis. 15-Lipoxygenase (15-LO) acts in physiological membrane remodeling and the pathogenesis of atherosclerosis, inflammation, and carcinogenesis. It is highly regulated and expressed in a tissue- and cell-type-specific fashion. IL-4 and IL-13 play important roles in transactivating the 15-LO gene. Overexpression of 15-LO type 1 in prostate cancer contributes to the cancer progression by regulating IGF-1R expression and activation.

    Gen-ID
    246
    UniProt
    P16050
    Pathways
    Regulation of Actin Filament Polymerization
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