ALOX15 Antikörper (AA 2-337)

Produktnummer ABIN3043726

Produktdetails anti-ALOX15 Antikörper

Target: ALOX15 (Arachidonate 15-Lipoxygenase (ALOX15))

Bindungsspezifität: AA 2-337

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ALOX15 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Verwendungszweck: Rabbit IgG polyclonal antibody for Arachidonate 15-lipoxygenase(ALOX15) detection. Tested with WB, IHC-P in Human.

Kreuzreaktivität (Details): No cross reactivity with other proteins.

Produktmerkmale: Rabbit IgG polyclonal antibody for Arachidonate 15-lipoxygenase(ALOX15) detection. Tested with WB, IHC-P in Human.
Gene Name: arachidonate 15-lipoxygenase
Protein Name: Arachidonate 15-lipoxygenase

Aufreinigung: Immunogen affinity purified.

Immunogen: E.coli-derived human ALOX15 recombinant protein (Position: G2-P337). Human ALOX15 shares 72% and 73% amino acid (aa) sequences identity with mouse and rat ALOX15, respectively.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human, The detection limit for ALOX15 is approximately 0.25 ng/lane under reducing conditions.
IHC-P: Concentration: 0.5-1 μg/mL, Tested Species: Human, Epitope Retrieval by Heat: Boiling the paraffin sections in 10 mM citrate buffer, pH 6.0, for 20 mins is required for the staining of formalin/paraffin sections.
Notes: Tested Species: Species with positive results. Other applications have not been tested. Optimal dilutions should be determined by end users.

Kommentare:

Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Konzentration: 500 μg/mL

Buffer: Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.

Details zu ALOX15

Target: ALOX15 (Arachidonate 15-Lipoxygenase (ALOX15))

Andere Bezeichnung: ALOX15 (ALOX15 Produkte)

Synonyme: 15-LOX-1 antikoerper, 15LOX-1 antikoerper, ALOX15 antikoerper, 12-LO antikoerper, Alox12l antikoerper, L-12LO antikoerper, 12-LOX antikoerper, Alox12 antikoerper, ALOX12 antikoerper, 15-LOX antikoerper, Alox12e antikoerper, arachidonate 15-lipoxygenase antikoerper, Arachidonate 15-lipoxygenase antikoerper, ALOX15 antikoerper, Alox15 antikoerper, Nmul_A0532 antikoerper, Sden_1680 antikoerper, Swoo_2919 antikoerper, PCC8801_3106 antikoerper, Cyan8802_3014 antikoerper, Nwat_1315 antikoerper

Hintergrund: Arachidonate 15-lipoxygenase, also known as 15 LOX or LOG15, is an enzyme that in humans is encoded by the ALOX15 gene. This gene is mapped to 17p13.2. It is found that ALOX15 is a mutator gene. ALOX15 gene product is implicated in antiinflammation, membrane remodeling, and cancer development/metastasis. Loss of the TP53 gene, or gain-of-function activities resulting from the expression of its mutant forms regulates ALOX15 promoter activity in human and in mouse, albeit in directionally opposite manners.

Synonyms: 15 lipoxygenase 1 antibody|15 LIPOXYGENASE RETICULOCYTE ARACHIDONATE antibody|15 LOX antibody|15 LOX 1 antibody|15-LOX antibody|15LOX 1 antibody|ALOX15 antibody|Arachidonate 15 lipoxygenase antibody|Arachidonate 15-lipoxygenase antibody|Arachidonate omega 6 lipoxygenase antibody|Arachidonate omega-6 lipoxygenase antibody|LOG15 antibody|LOX15_HUMAN antibody

Gen-ID: 246

UniProt: P16050

Pathways: Regulation of Actin Filament Polymerization