SOCS6 Antikörper (AA 21-120) (HRP)

Produktnummer ABIN6987494

Der Kaninchen-Polyklonal Anti-SOCS6-Antikörper wurde für WB, ELISA, IHC (p) und IHC (fro) validiert. Er ist geeignet zum Nachweis von SOCS6 in Proben aus Maus und Huhn. }

Kurzübersicht für SOCS6 Antikörper (AA 21-120) (HRP) (ABIN6987494)

Target: SOCS6 (Suppressor of Cytokine Signaling 6 (SOCS6))

Reaktivität: Maus, Huhn

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SOCS6 Antikörper ist konjugiert mit HRP

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Produktdetails anti-SOCS6 Antikörper (HRP)

Bindungsspezifität: AA 21-120

Kreuzreaktivität: Huhn, Maus

Homologie: Human,Rat,Dog,Cow,Sheep,Pig,Horse,Rabbit

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human SOCS6

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:300-5000
IHC-P 1:200-400
IHC-F 1:100-500

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Haltbarkeit: 12 months

Details zu SOCS6

Target: SOCS6 (Suppressor of Cytokine Signaling 6 (SOCS6))

Andere Bezeichnung: SOCS6

Hintergrund:

Synonyms: CIS-4, CIS4, Cish4, Cytokine inducible SH2 protein 4, Cytokine-inducible SH2 protein 4, HSPC060, SOCS-4, SOCS-6, SOCS4, Socs6, SOCS6_HUMAN, SSI4, STAI4, STAT induced STAT inhibitor 4, STAT4, STATI4, Suppressor of cytokine signaling 4, Suppressor of cytokine signaling 6.

Background: The protein encoded by this gene contains a SH2 domain and a CIS homolog domain. The protein thus belongs to the cytokine-induced STAT inhibitor (CIS), also known as suppressor of cytokine signaling (SOCS) or STAT-induced STAT inhibitor (SSI), protein family. CIS family members are known to be cytokine-inducible negative regulators of cytokine signaling. The expression of this gene can be induced by GM-CSF and EPO in hematopoietic cells. A high expression level of this gene was found in factor-independent chronic myelogenous leukemia (CML) and erythroleukemia (HEL) cell lines. [provided by RefSeq, Jul 2008].

Gen-ID: 9306

UniProt: O14544

Pathways: JAK-STAT Signalweg, Carbohydrate Homeostasis