CDK7 Antikörper (pThr170) (Cy5)

Produktnummer ABIN6984109

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch CDK7 in WB, IF (cc) und IF (p). Er zeigt eine Reaktivität gegenüber Human.

Kurzübersicht für CDK7 Antikörper (pThr170) (Cy5) (ABIN6984109)

Target: CDK7 (Cyclin-Dependent Kinase 7 (CDK7))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CDK7 Antikörper ist konjugiert mit Cy5

Applikation: Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Produktdetails anti-CDK7 Antikörper (Cy5)

Bindungsspezifität: pThr170

Kreuzreaktivität: Human

Homologie: Mouse,Rat,Dog,Pig,Horse,Rabbit

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated Synthesised phosphopeptide derived from human CDK7 around the phosphorylation site of Thr170

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Haltbarkeit: 12 months

Details zu CDK7

Target: CDK7 (Cyclin-Dependent Kinase 7 (CDK7))

Andere Bezeichnung: CDK7

Hintergrund:

Synonyms: CDK7 (phospho Thr170), CDK7 (phospho T170), Cyclin H, MAT1, Cyclin Dependent Kinase 7, CAK1, MO15, CDKN7, serine/threonine kinase, STK1, serine/threonine protein kinase 1, MO15 homolog,Xenopus laevis, cdk-activating kinase, Cdk-activating kinase, serine/threonine protein kinase MO15, homolog of Xenopus MO15 Cdk-activating kinase, kinase subunit of CAK, 39 KDa protein kinase, CR4 protein kinase, CRK4, CDK7_HUMAN.

Background: The protein encoded by this gene is a member of the cyclin-dependent protein kinase (CDK) family. CDK family members are highly similar to the gene products of Saccharomyces cerevisiae cdc28, and Schizosaccharomyces pombe cdc2, and are known to be important regulators of cell cycle progression. This protein forms a trimeric complex with cyclin H and MAT1, which functions as a Cdk-activating kinase (CAK). It is an essential component of the transcription factor TFIIH, that is involved in transcription initiation and DNA repair. This protein is thought to serve as a direct link between the regulation of transcription and the cell cycle.

Gen-ID: 1022

UniProt: P50613

Pathways: Zellzyklus, DNA Reparatur, Intracellular Steroid Hormone Receptor Signaling Pathway, Mitotic G1-G1/S Phases, M Phase