Survivin Antikörper (AbBy Fluor® 350)
Kurzübersicht für Survivin Antikörper (AbBy Fluor® 350) (ABIN6976368)
Target
Alle Survivin (BIRC5) Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
Klon
-
-
Kreuzreaktivität
- Human, Ratte
-
Aufreinigung
- Purified by Protein A.
-
Immunogen
- Recombinant human Survivin
-
Isotyp
- IgG
-
-
-
-
Applikationshinweise
- IF(ICC) 1:50-200
-
Beschränkungen
- Nur für Forschungszwecke einsetzbar
-
-
-
Format
- Liquid
-
Konzentration
- 1 μg/μL
-
Buffer
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
-
Konservierungsmittel
- ProClin
-
Vorsichtsmaßnahmen
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
-
Lagerung
- -20 °C
-
Informationen zur Lagerung
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
-
Haltbarkeit
- 12 months
-
-
- Survivin (BIRC5) (Baculoviral IAP Repeat-Containing 5 (BIRC5))
-
Andere Bezeichnung
- Survivin
-
Hintergrund
-
Synonyms: API4, API-4, API 4, Survivin variant 3 alpha, Apoptosis Inhibitor 4, Apoptosis inhibitor survivin, Apoptosis inhibitor4, Baculoviral IAP repeat containing 5, Baculoviral IAP repeat containing protein 5, Baculoviral IAP repeat-containing protein 5, BIRC 5, BIRC5, BIRC-5, EPR 1, EPR-1, IAP4, IAP-4, IAP 4, SVV, TIAP, BIRC5_HUMAN.??
Background: May play a role in neoplasia. May counteract a default induction of apoptosis in G2/M phase. Interacts with tubulin. Inhibitor of caspase-3 and caspase-7. Component of the chromosomal passenger complex (CPC), a complex that acts as a key regulator of mitosis. The CPC complex has essential functions at the centromere in ensuring correct chromosome alignment and segregation and is required for chromatin-induced microtubule stabilization and spindle assembly. Belongs to the IAP family.?
-
Gen-ID
- 332
-
UniProt
- O15392
-
Pathways
- Apoptose, Zellzyklus, Nuclear Hormone Receptor Binding
Target
-