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TDG Antikörper

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch TDG in WB. Er zeigt eine Reaktivität gegenüber Maus.
Produktnummer ABIN6972851

Kurzübersicht für TDG Antikörper (ABIN6972851)

Target

Alle TDG Antikörper anzeigen
TDG (Thymine-DNA Glycosylase (TDG))

Reaktivität

  • 51
  • 18
  • 11
  • 2
  • 2
Maus

Wirt

  • 38
  • 12
Kaninchen

Klonalität

  • 41
  • 10
Polyklonal

Konjugat

  • 44
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Dieser TDG Antikörper ist unkonjugiert

Applikation

  • 40
  • 14
  • 11
  • 11
  • 6
  • 6
  • 5
  • 3
  • 3
  • 2
  • 1
Western Blotting (WB)
  • Produktmerkmale

    In the DNA of higher eukaryotes, hydrolytic deamination of 5-methylcytosine to thymine leads to the formation of G/T mismatches. In addition, TET proteins oxidize 5- methylcytosine (5mC) to 5-hydroxymethylcytosine (5hmC), 5- formylcytosine (5fC), and 5-carboxylcytosine (5caC). TDG / Thymine-DNA glycosylase functions to correct G/T mispairs to G/C pairs and plays a role in active DNA demethylation by recognizing 5fC and 5caC and converting these to cystosine through the base excision repair (BER) pathway. TDG / Thymine-DNA glycosylase antibody (pAb) was raised in a Rabbit host. It has been validated for use in Western blot, it has been shown to react with Mouse samples.

    Aufreinigung

    Protein A Chromatography

    Immunogen

    This antibody was raised against a full-length recombinant protein corresponding to mouse thymine DNA glycosylase (TDG).

    Isotyp

    IgG
  • Applikationshinweise

    Optimal working dilution should be determined by the investigator.

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Buffer

    Purified IgG in PBS with 30 % glycerol and 0.035 % sodium azide.

    Konservierungsmittel

    Sodium azide

    Vorsichtsmaßnahmen

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Lagerung

    -20 °C

    Informationen zur Lagerung

    Avoid repeated freeze/thaw cycles by aliquoting items into single-use fractions for storage at -20°C for up to 2 years. Keep all reagents on ice when not in storage.
  • Target

    TDG (Thymine-DNA Glycosylase (TDG))

    Andere Bezeichnung

    TDG / Thymine-DNA glycosylase

    Molekulargewicht

    55 kDa

    NCBI Accession

    NP_766140

    Pathways

    DNA Reparatur, Chromatin Binding
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