GLI1 Antikörper (C-Term)

Produktnummer ABIN6971684

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch GLI1 in WB. Er zeigt eine Reaktivität gegenüber Human.

Kurzübersicht für GLI1 Antikörper (C-Term) (ABIN6971684)

Target: GLI1 (Zinc Finger Protein GLI1 (GLI1))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser GLI1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-GLI1 Antikörper

Bindungsspezifität: C-Term

Produktmerkmale: GLI1 (Glioma-associated oncogene 1) is a zinc finger transcription factor and oncogene. GLI1 is part of the hedgehog signaling pathway, but is also activated in response to TGF-b signaling as well. GLI1 activates transcription of a number of genes that promote cell cycle progression. GLI1 is overexpressed as a result of constitutive activation of hedgehog signaling, which plays a role in the initiation of cancer. GLI1 also promotes self-renewal of neural stem cells. GLI1 antibody (pAb) was raised in a Rabbit host. It has been validated for use in Western blot, it has been shown to react with Human samples.

Aufreinigung: Affinity Purified

Immunogen: This GLI1 antibody was raised against a peptide within the C-terminal region of human GLI1.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: Purified IgG in PBS with 30 % glycerol and 0.035 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Avoid repeated freeze/thaw cycles by aliquoting items into single-use fractions for storage at -20°C for up to 2 years. Keep all reagents on ice when not in storage.

Details zu GLI1

Target: GLI1 (Zinc Finger Protein GLI1 (GLI1))

Andere Bezeichnung: GLI1

Molekulargewicht: 120 kDa

NCBI Accession: NP_005260

Pathways: Hedgehog Signalweg, Dopaminergic Neurogenesis