H2AFZ Antikörper (acLys7)

Produktnummer ABIN6952411

Dieses Anti-H2AFZ-Antikörper ist ein Kaninchen Monoklonal-Antikörper zur Detektion von H2AFZ in WB, IF, ChIP und ChIP-seq. Geeignet für Human.

Kurzübersicht für H2AFZ Antikörper (acLys7) (ABIN6952411)

Target: H2AFZ (H2A Histone Family, Member Z (H2AFZ))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Monoklonal

Konjugat: Dieser H2AFZ Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunofluorescence (IF), Chromatin Immunoprecipitation (ChIP), ChIP DNA-Sequencing (ChIP-seq)

Produktdetails anti-H2AFZ Antikörper

Bindungsspezifität: acLys7

Spezifität: Monoclonal antibody raised in rabbit against histone H2A.Z acetylated at Lys7 (H2A.ZK7ac), using a KLHconjugated synthetic peptide.

Aufreinigung: Protein A purified

Immunogen: synthetic peptide

Anwendungsinformationen

Applikationshinweise: ChIP/ChIP-seq 1 μg:ChIP
WB 1:2,000
IF 1:500

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: PBS, 50 % glycerol, 1 % BSA , 0.05 % azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Details zu H2AFZ

Target: H2AFZ (H2A Histone Family, Member Z (H2AFZ))

Andere Bezeichnung: H2A.Z

Hintergrund: Histones are the main constituents of the protein part of chromosomes of eukaryotic cells. They are rich in the amino acids arginine and lysine and have been greatly conserved during evolution. Histones pack the DNA into tight masses of chromatin. Two core histones of each class H2A, H2B, H3 and H4 assemble and are wrapped by 146 base pairs of DNA to form one octameric nucleosome. Histone tails undergo numerous post-translational modifications, which either directly or indirectly alter chromatin structure to facilitate transcriptional activation or repression or other nuclear processes. In addition to the genetic code, combinations of the different histone modifications reveal the so-called "histone code". Histone methylation and demethylation is dynamically regulated by respectively histone methyl transferases and histone demethylases. Acetylation of H2A.ZK7 is associated with gene activation.

UniProt: P0C0S5

Pathways: Telomere Maintenance