H2AFZ Antikörper (C-Term)

Produktnummer ABIN6952409

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch H2AFZ in WB, ELISA, IF, ChIP und ChIP-seq. Er zeigt eine Reaktivität gegenüber Human.

Kurzübersicht für H2AFZ Antikörper (C-Term) (ABIN6952409)

Target: H2AFZ (H2A Histone Family, Member Z (H2AFZ))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser H2AFZ Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunofluorescence (IF), Chromatin Immunoprecipitation (ChIP), ChIP DNA-Sequencing (ChIP-seq)

Produktdetails anti-H2AFZ Antikörper

Bindungsspezifität: C-Term

Spezifität: Polyclonal antibody raised in rabbit against histone variant H2A.Z, using a KLH-conjugated synthetic peptide containing a sequence from the C-terminal part of the protein.

Kreuzreaktivität: Maus

Kreuzreaktivität (Details): broad range

Aufreinigung: Peptide affinity purified

Immunogen: synthetic peptide

Anwendungsinformationen

Applikationshinweise: ChIP 0.5 - 1 μg:ChIP
ELISA 1:5,000
WB 1:1,000
F 1:500

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1.55 μg/μL

Buffer: PBS, 0.05 % azide, 0.05 % ProClin300

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Details zu H2AFZ

Target: H2AFZ (H2A Histone Family, Member Z (H2AFZ))

Andere Bezeichnung: H2A.Z

Hintergrund: Histones are the main constituents of the protein part of chromosomes of eukaryotic cells. They are rich in the amino acids arginine and lysine and have been greatly conserved during evolution. Histones pack the DNA into tight masses of chromatin. Two core histones of each class H2A, H2B, H3 and H4 assemble and are wrapped by 146 base pairs of DNA to form one octameric nucleosome. Histone tails undergo numerous post-translational modifications, which either directly or indirectly alter chromatin structure to facilitate transcriptional activation or repression or other nuclear processes. In addition to the genetic code, combinations of the different histone modifications reveal the so-called "histone code". Histone methylation and demethylation is dynamically regulated by respectively histone methyl transferases and histone demethylases. Histone variant H2A.Z is associated with the active genes.

UniProt: P0C0S5

Pathways: Telomere Maintenance