Growth Hormone 1 Antikörper

Produktnummer ABIN6950857

Der Maus Monoklonal anti-Growth Hormone 1 Antikörper wird verwendet zum Nachweis von Growth Hormone 1 in Proben von Human. Er wurde validiert für IHC.

Kurzübersicht für Growth Hormone 1 Antikörper (ABIN6950857)

Target: Growth Hormone 1 (GH1)

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser Growth Hormone 1 Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (IHC)

Produktdetails anti-Growth Hormone 1 Antikörper

Verwendungszweck: GH/ hPL mouse mAb

Spezifität: The antibody can recognize human Placental lactogen, and has cross-reactiin with GH protein.

Aufreinigung: The antibody was purified by affinity chromatography using a specific immunogen.

Immunogen: A synthetic peptide corresponding to the amino acid region 150 - 217 of the human GH/ hPL protein.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IHC, 1:200-1:400

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: The antibody is provided in liquid form in phosphate - buffered saline with 50 % glycerol, 0.05 % BSA, and 0.05 % Proclin 300.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid freeze / thaw cycles

Lagerung: -20 °C

Informationen zur Lagerung: Store at-20°C. Avoid freeze / thaw cycles.

Details zu Growth Hormone 1

Target: Growth Hormone 1 (GH1)

Andere Bezeichnung: Growth Hormone (GH)

Hintergrund:

Synonyms: Lactogen, Placental lactogen, PL, hPL, gH, GH-N, GH1, GHB5, GHN, Growth hormone 1, Growth hormone, Growth hormone B5, Growth hormone, normal, Growth hormone, pituitary, HG1, hGH-N, IGHD1B, Pituitary growth hormone, RNGHGP, SOMA_HUMAN, Somatotropin

Background: Human placental prolactin (HPL) is a 22 kD polypeptide hormone synthesized and secreted by placental syncytiotrophoblast cells, has partial homology with growth hormone. It is expressed in normal placenta, choriocarcinoma, testicular cancer. Anti-HPL antibody is commonly used in the study of trophoblastic tumors. Growth hormone (GH) is a hormone synthesized and secreted by growth hormone cells in the anterior pituitary, which can promote protein synthesis and bone development. The mechanism of stimulating body growth is to stimulate the secretion of IGF-1 by liver and other tissues. It is mainly used for the functional classification of pituitary tumor and the differentiation of primary pituitary tumor and metastatic cancer.

Gene Name: CSH1 CSH2 GH1

Protein Name: GH/ hPL

UniProt: P01241

Pathways: NF-kappaB Signalweg, JAK-STAT Signalweg, Intracellular Steroid Hormone Receptor Signaling Pathway, Peptide Hormone Metabolism, Regulation of Intracellular Steroid Hormone Receptor Signaling, Regulation of Hormone Metabolic Process, Response to Growth Hormone Stimulus, Regulation of Hormone Biosynthetic Process