WEE1 Antikörper (AA 151-250) (Cy7)
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- Target Alle WEE1 Antikörper anzeigen
- WEE1 (WEE1 Homolog (S. Pombe) (WEE1))
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Bindungsspezifität
- AA 151-250
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Reaktivität
- Human, Ratte
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser WEE1 Antikörper ist konjugiert mit Cy7
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Applikation
- Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
- Kreuzreaktivität
- Human, Ratte
- Homologie
- Mouse
- Aufreinigung
- Purified by Protein A.
- Immunogen
- KLH conjugated synthetic peptide derived from human WEE1
- Isotyp
- IgG
- Top Product
- Discover our top product WEE1 Primärantikörper
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anti-WEE1 Homolog (S. Pombe) (WEE1) (pSer642) antibody
WEE1 Reaktivität: Human WB, ELISA, IF (cc), IF (p), IHC (p), IHC (fro) Wirt: Kaninchen Polyclonal unconjugated
anti-WEE1 Homolog (S. Pombe) (WEE1) (pSer123) antibodyWEE1 Reaktivität: Maus WB, ELISA, IF (cc), IF (p), IHC (p), IHC (fro) Wirt: Kaninchen Polyclonal unconjugated
anti-WEE1 Homolog (S. Pombe) (WEE1) (pSer123) antibodyWEE1 Reaktivität: Human IHC (p), DB Wirt: Kaninchen Polyclonal RB07865 unconjugated
anti-WEE1 Homolog (S. Pombe) (WEE1) (AA 289-388) antibodyWEE1 Reaktivität: Human WB, ELISA Wirt: Maus Monoclonal 5B6 unconjugated
anti-WEE1 Homolog (S. Pombe) (WEE1) (AA 144-173) antibodyWEE1 Reaktivität: Human WB, IHC (p) Wirt: Kaninchen Polyclonal RB3524 unconjugated
anti-WEE1 Homolog (S. Pombe) (WEE1) (AA 604-634), (C-Term) antibodyWEE1 Reaktivität: Human WB, IHC (p) Wirt: Kaninchen Polyclonal RB3525 unconjugated
anti-WEE1 Homolog (S. Pombe) (WEE1) (AA 1-646) antibodyWEE1 Reaktivität: Human WB, PLA Wirt: Kaninchen Polyclonal unconjugated
anti-WEE1 Homolog (S. Pombe) (WEE1) (AA 1-646) antibodyWEE1 Reaktivität: Human WB, IF Wirt: Maus Polyclonal unconjugated
anti-WEE1 Homolog (S. Pombe) (WEE1) (AA 604-634) antibodyWEE1 Reaktivität: Human WB, ELISA, IHC Wirt: Kaninchen Polyclonal unconjugated
anti-WEE1 Homolog (S. Pombe) (WEE1) (pSer123) antibodyWEE1 Reaktivität: Human ELISA, IHC, DB Wirt: Kaninchen Polyclonal unconjugated
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- Applikationshinweise
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IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 - Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- 1 μg/μL
- Buffer
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
- Konservierungsmittel
- ProClin
- Vorsichtsmaßnahmen
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
- Haltbarkeit
- 12 months
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- Target
- WEE1 (WEE1 Homolog (S. Pombe) (WEE1))
- Andere Bezeichnung
- WEE1 (WEE1 Produkte)
- Hintergrund
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Synonyms: DKFZp686I18166, EC 2.7.10.2, FLJ16446, Wee 1, WEE-1, WEE1 protein, Wee1 homolog, WEE1 homolog S. pombe, Wee1 like protein kinase, Wee1 tyrosine kinase, Wee1+ homolog, Wee1+ S. pombe homolog, WEE1A, Wee1A kinase, WEE1hu, WEE1 tyrosine kinase isoform 1, MGC105683, WEE1_HUMAN.
Background: This gene encodes a nuclear protein, which is a tyrosine kinase belonging to the Ser/Thr family of protein kinases. Acts as a negative regulator of entry into mitosis (G2 to M transition) by protecting the nucleus from cytoplasmically activated cyclin B1-complexed CDK1 before the onset of mitosis by mediating phosphorylation of CDK1 on 'Tyr-15'. Specifically phosphorylates and inactivates cyclin B1-complexed CDK1 reaching a maximum during G2 phase and a minimum as cells enter M phase. Phosphorylation of cyclin B1-CDK1 occurs exclusively on 'Tyr-15' and phosphorylation of monomeric CDK1 does not occur. Its activity increases during S and G2 phases and decreases at M phase when it is hyperphosphorylated. A correlated decrease in protein level occurs at M/G1 phase, probably due to its degradation.
- Gen-ID
- 7465
- UniProt
- P30291
- Pathways
- Zellzyklus, Mitotic G1-G1/S Phases, M Phase
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