MECP2 Antikörper
Kurzübersicht für MECP2 Antikörper (ABIN6944061)
Target
Alle MECP2 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Kreuzreaktivität
- Human
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Aufreinigung
- Affinity purified polyclonal antibody in PBS containing 0.05% azide and 0.05% ProClin 300.
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Immunogen
- Polyclonal antibody raised in rabbit against MeCP2 (Methyl-CpG-binding domain protein 2), using a KLH-conjugated synthetic peptide containing a sequence from the C-terminal part of the protein
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Applikationshinweise
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WB 1:300-5000
ELISA 1:500-1000
dot-blot() -
Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- 1.2 μg/μL
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Buffer
- PBS with 0.05 % sodium azide and 0.05 % Proclin300.
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Konservierungsmittel
- ProClin
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Vorsichtsmaßnahmen
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- Store at -20°C for 12 months.
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Haltbarkeit
- 12 months
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- MECP2 (Methyl CpG Binding Protein 2 (MECP2))
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Andere Bezeichnung
- MeCP2
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Hintergrund
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Synonyms: Methyl-CpG-binding protein 2, MECP2, MeCp-2 protein
Background: Chromosomal protein that binds to methylated DNA. It can bind specifically to a single methyl-CpG pair. It is not influenced by sequences flanking the methyl-CpGs. Mediates transcriptional repression through interaction with histone deacetylase and the corepressor SIN3A. Binds both 5-methylcytosine (5mC) and 5-hydroxymethylcytosine (5hmC)-containing DNA, with a preference for 5-methylcytosine (5mC).
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Gen-ID
- 4204
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UniProt
- P51608
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Pathways
- Inositol Metabolic Process, Chromatin Binding, Synaptic Membrane
Target
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