BCL10 Antikörper (C-Term)
Kurzübersicht für BCL10 Antikörper (C-Term) (ABIN6942238)
Target
Alle BCL10 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
Klon
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Bindungsspezifität
- C-Term
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Verwendungszweck
- Bcl10 Recombinant Antibody
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Kreuzreaktivität
- Human
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Aufreinigung
- Purified by Protein A.
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Immunogen
- Recombinant human Bcl10 protein, around C-terminal 200aa.
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Isotyp
- IgG
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Applikationshinweise
- WB(1:300-5000), IHC-P(1:200-400), IHC-F(1:100-500), IF(), Flow-Cyt(1 μg/Test), ICC/IF(1:50-100)
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- Lot specific
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Buffer
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
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Konservierungsmittel
- ProClin
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Vorsichtsmaßnahmen
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- Store at -20°C for 12 months.
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Haltbarkeit
- 12 months
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- BCL10 (B-Cell CLL/lymphoma 10 (BCL10))
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Andere Bezeichnung
- Bcl10
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Hintergrund
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Synonyms: CLAP, mE10, CIPER, IMD37, c-E10, CARMEN, B-cell lymphoma/leukemia 10, B-cell CLL/lymphoma 10, Bcl-10, CARD-containing molecule enhancing NF-kappa-B, CARD-like apoptotic protein, hCLAP, CED-3/ICH-1 prodomain homologous E10-like regulator, Cellular homolog of vCARMEN, cCARMEN, Cellular-E10, Mammalian CARD-containing adapter molecule E10, BCL10
Background: Involved in adaptive immune response (PubMed:25365219). Promotes apoptosis, pro-caspase-9 maturation and activation of NF-kappa-B via NIK and IKK. May be an adapter protein between upstream TNFR1-TRADD-RIP complex and the downstream NIK-IKK-IKAP complex. Is a substrate for MALT1 (PubMed:18264101).
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Gen-ID
- 8915
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UniProt
- O95999
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Pathways
- T-Zell Rezeptor Signalweg, Fc-epsilon Rezeptor Signalübertragung, Activation of Innate immune Response, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Tube Formation, Positive Regulation of Endopeptidase Activity, BCR Signaling, Ubiquitin Proteasome Pathway, S100 Proteine
Target
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