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Growth Hormone 1 Antikörper (AA 58-187)

Dieses Maus Monoklonal-Antikörper erkennt spezifisch Growth Hormone 1 in IHC und StM. Er zeigt eine Reaktivität gegenüber Human.
Produktnummer ABIN6939510

Kurzübersicht für Growth Hormone 1 Antikörper (AA 58-187) (ABIN6939510)

Target

Alle Growth Hormone 1 (GH1) Antikörper anzeigen
Growth Hormone 1 (GH1)

Reaktivität

  • 136
  • 20
  • 14
  • 11
  • 8
  • 8
  • 6
  • 4
  • 3
  • 3
  • 2
  • 2
  • 1
  • 1
Human

Wirt

  • 86
  • 80
  • 2
  • 1
  • 1
Maus

Klonalität

  • 98
  • 72
Monoklonal

Konjugat

  • 102
  • 13
  • 4
  • 4
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Dieser Growth Hormone 1 Antikörper ist unkonjugiert

Applikation

  • 92
  • 91
  • 39
  • 38
  • 30
  • 22
  • 20
  • 13
  • 13
  • 13
  • 12
  • 9
  • 7
  • 6
  • 6
  • 5
  • 4
  • 4
  • 3
  • 3
  • 1
  • 1
  • 1
  • 1
  • 1
Immunohistochemistry (IHC), Staining Methods (StM)

Klon

GH-1371
  • Bindungsspezifität

    • 25
    • 20
    • 7
    • 6
    • 6
    • 4
    • 4
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    AA 58-187

    Aufreinigung

    Purified by Protein A/G

    Immunogen

    A recombinant fragment (around aa58-187) of human Growth Hormone (GH) protein (exact sequence is proprietary)

    Isotyp

    IgG2b kappa
  • Applikationshinweise

    Positive Control: Pituitary cells. Human pituitary tissue (IHC).

    Known Application: Immunohistochemistry (Formalin-fixed) (1-2 μg/mL for 30 min at RT)(Staining of formalin-fixed tissues requires boiling tissue sections in 10 mM Citrate Buffer, pH 6.0, for 10-20 min followed by cooling at RT for 20 minutes)Optimal dilution for a specific application should be determined.

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Konzentration

    200 μg/mL

    Buffer

    10 mM PBS with 0.05 % BSA & 0.05 % azide.

    Konservierungsmittel

    Sodium azide

    Vorsichtsmaßnahmen

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Lagerung

    4 °C,-80 °C

    Informationen zur Lagerung

    Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

    Haltbarkeit

    24 months
  • Target

    Growth Hormone 1 (GH1)

    Andere Bezeichnung

    GH1

    Hintergrund

    Pituitary growth hormone (GH) plays a crucial role in stimulating and controlling the growth, metabolism and differentiation of many mammalian cell types by modulating the synthesis of multiple mRNA species. These effects are mediated by the binding of GH to its membrane-bound receptor, GHR, and involve a phosphorylation cascade that results in the modulation of numerous signaling pathways. GH is synthesized by acidophilic or somatotropic cells of the anterior pituitary gland. Anti-GH is a useful marker in classification of pituitary tumors and the study of pituitary disease (acromegaly).

    Molekulargewicht

    20kDa

    Gen-ID

    2688

    UniProt

    P01241

    Pathways

    NF-kappaB Signalweg, JAK-STAT Signalweg, Intracellular Steroid Hormone Receptor Signaling Pathway, Peptide Hormone Metabolism, Regulation of Intracellular Steroid Hormone Receptor Signaling, Regulation of Hormone Metabolic Process, Response to Growth Hormone Stimulus, Regulation of Hormone Biosynthetic Process
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