TRIM29 Antikörper (AA 1-200)

Produktnummer ABIN6939435

Dieses Maus Monoklonal-Antikörper erkennt spezifisch TRIM29 in WB, ELISA und Coat. Er zeigt eine Reaktivität gegenüber Human.

Kurzübersicht für TRIM29 Antikörper (AA 1-200) (ABIN6939435)

Target: TRIM29 (Tripartite Motif Containing 29 (TRIM29))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser TRIM29 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Coating (Coat)

Klon: TRIM29-1042

Produktdetails anti-TRIM29 Antikörper

Bindungsspezifität: AA 1-200

Spezifität: It recognizes a 66 kDa protein, which is identified as Tripartite motif-containing protein 29 (TRIM29). It interacts with the intermediate filament protein vimentin, a substrate for the PKC family of protein kinases, and with hPKCI-1, an inhibitor of the PKCs. TRIM29 protein contains both zinc finger and leucine zipper motifs, suggesting that the it may form homodimers and possibly associate with DNA. High expression of TRIM29 has been reported in gastric cancer and pancreatic cancer, and correlates with enhanced tumor growth and lymph node metastasis. TRIM29 is also able to distinguish lung squamous cell carcinoma from lung adenocarcinoma with ~90 % positive accuracy, when used in a panel with TTF-1, p63, CK5/6, and Napsin-A antibodies.

Aufreinigung: Purified by Protein A/G

Immunogen: Recombinant fragment (126 Amino acid residues between aa 1-200) of human TRIM29 protein

Isotyp: IgG2b kappa

Anwendungsinformationen

Applikationshinweise:

Positive Control: A431 cell lysate. Human tonsil or squamous cell carcinoma.

Known Application: ELISA (For coating, order Ab without BSA), Western Blot (0.5-1 μg/mL), Optimal dilution for a specific application should be determined.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 200 μg/mL

Buffer: 10 mM PBS with 0.05 % BSA & 0.05 % azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-80 °C

Informationen zur Lagerung: Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Haltbarkeit: 24 months

Details zu TRIM29

Target: TRIM29 (Tripartite Motif Containing 29 (TRIM29))

Andere Bezeichnung: TRIM29

Molekulargewicht: 66kDa

Gen-ID: 23650

UniProt: Q14134

Pathways: p53 Signalweg, Apoptose, DNA Reparatur, Inositol Metabolic Process, Positive Regulation of Response to DNA Damage Stimulus