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GJB1 Antikörper

GJB1 Reaktivität: Human IHC (f) Wirt: Maus Monoclonal GJB1-1753 unconjugated
Produktnummer ABIN6937323
  • Target Alle GJB1 Antikörper anzeigen
    GJB1 (Gap Junction Protein, beta 1, 32kDa (GJB1))
    Reaktivität
    • 71
    • 67
    • 53
    • 6
    • 4
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    Human
    Wirt
    • 52
    • 23
    • 11
    Maus
    Klonalität
    • 52
    • 34
    Monoklonal
    Konjugat
    • 42
    • 5
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser GJB1 Antikörper ist unkonjugiert
    Applikation
    • 49
    • 32
    • 26
    • 24
    • 21
    • 20
    • 13
    • 13
    • 7
    • 7
    • 2
    • 1
    • 1
    • 1
    Immunohistochemistry (Formalin-fixed Sections) (IHC (f))
    Spezifität
    This Ab recognizes a protein of 27-32kDa, identified as Connexin 32. The connexin family of proteins forms hexameric complexes called 'connexons' that facilitate movement of low molecular weight proteins between cells via gap junctions. Connexin proteins share a common topology of four transmembrane therefore, one connexin usually cannot fully substitute for another.
    Kreuzreaktivität (Details)
    Human. Mouse. Rat.
    Aufreinigung
    1.0mg/ml of Ab purified from Bioreactor by Protein A/G.
    Immunogen
    Recombinant human GJB1 protein
    Klon
    GJB1-1753
    Isotyp
    IgG
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  • Applikationshinweise

    Known_Application: Immunohistochemistry (Formalin-fixed) (0.1-0.2 μg/mL for 30 min at RT)(Staining of formalin-fixed tissues requires heating tissue sections in 10 mM Tris with 1 mM EDTA, pH 9.0, for 45 min at 95°C followed by cooling at RT for 20 minutes), Optimal dilution for a specific application should be determined.

    Positive_Control: MCF-7 cells. Liver, Kidney, Stomach or Tonsil.

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Konzentration
    1.0 mg/mL
    Buffer
    Prepared in 10 mM PBS, WITHOUT BSA and Azide.
    Konservierungsmittel
    Azide free
    Lagerung
    -20 °C,-80 °C
    Informationen zur Lagerung
    Antibody without azide store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.
    Haltbarkeit
    24 months
  • Target
    GJB1 (Gap Junction Protein, beta 1, 32kDa (GJB1))
    Andere Bezeichnung
    GJB1 (GJB1 Produkte)
    Hintergrund
    Charcot Marie Tooth neuropathy X linked, CMTX, CMTX1, Connexin-32, Cx32, GAP junction 28 kDa liver protein, Gap junction beta-1 protein, Gap junction protein beta 1 32kD, GJB1,Connexin 32 (Gap Junction Protein)
    Cellular localisation: Cytoplasmic and Cell Surface
    Molekulargewicht
    27-32kDa
    Gen-ID
    2705, 333303
    UniProt
    P08034
    Pathways
    Cell-Cell Junction Organization
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