EGFR Antikörper
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- Target Alle EGFR Antikörper anzeigen
- EGFR (Epidermal Growth Factor Receptor (EGFR))
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Reaktivität
- Human
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Wirt
- Maus
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Klonalität
- Monoklonal
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Konjugat
- Dieser EGFR Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), Immunoprecipitation (IP)
- Spezifität
- This MAb reacts with a cytoplasmic domain of EGFR. EGFR is a type I receptor tyrosine kinase with sequence homology to erbB-1, -2, -3 -4 or HER-1, -2, -3 -4. It binds to Epidermal Growth Factor (EGF), Transforming Growth Factor-a (TGF-a), Heparin-binding EGF (HB-EGF), amphiregulin, betacellulin epiregulin.
- Keine Kreuzreaktivität
- Maus, Ratte (Rattus)
- Kreuzreaktivität (Details)
- Human. Does not react with Mouse or Rat.
- Aufreinigung
- 1.0mg/ml of Ab purified from Bioreactor by Protein A/G.
- Immunogen
- Purified EGFR from A431 cells.
- Klon
- H9B4
- Isotyp
- IgG1 kappa
- Top Product
- Discover our top product EGFR Primärantikörper
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- Applikationshinweise
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Known_Application: Immunoprecipitation (1-2 μg/500 μg protein lysate), Western Blot (1-2 μg/mL for 2 hours at RT), Optimal dilution for a specific application should be determined.
Positive_Control: A431 cells, Breast or Bladder cancer.
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Konzentration
- 1.0 mg/mL
- Buffer
- Prepared in 10 mM PBS, WITHOUT BSA and Azide.
- Konservierungsmittel
- Azide free
- Lagerung
- -20 °C,-80 °C
- Informationen zur Lagerung
- Antibody without azide store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.
- Haltbarkeit
- 24 months
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- Target
- EGFR (Epidermal Growth Factor Receptor (EGFR))
- Andere Bezeichnung
- EGFR (EGFR Produkte)
- Hintergrund
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Erbb1, ERBB1, Errp, HER1, mENA, PIG61, Proto-oncogene c-ErbB-1, Receptor Tyrosine Protein Kinase, ErbB1, Urogastrone, wa2, Wa5,EGFR (Epidermal Growth Factor Receptor)
Cellular localisation: Cell surface - Molekulargewicht
- ~170kDa (wild type) and ~145kDa (vIII variant)
- Gen-ID
- 1956, 488293
- UniProt
- P00533
- Pathways
- NF-kappaB Signalweg, RTK Signalweg, Fc-epsilon Rezeptor Signalübertragung, EGFR Signaling Pathway, Neurotrophin Signalübertragung, Stem Cell Maintenance, Hepatitis C, Positive Regulation of Response to DNA Damage Stimulus, Interaction of EGFR with phospholipase C-gamma, Thromboxane A2 Receptor Signaling, EGFR Downregulation, S100 Proteine
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