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EGFR Antikörper

EGFR Reaktivität: Human WB, IP Wirt: Maus Monoclonal H9B4 unconjugated
Produktnummer ABIN6937133
  • Target Alle EGFR Antikörper anzeigen
    EGFR (Epidermal Growth Factor Receptor (EGFR))
    Reaktivität
    • 762
    • 299
    • 287
    • 25
    • 25
    • 24
    • 20
    • 14
    • 8
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Human
    Wirt
    • 581
    • 178
    • 14
    • 13
    • 5
    • 4
    • 1
    • 1
    Maus
    Klonalität
    • 543
    • 249
    • 2
    Monoklonal
    Konjugat
    • 416
    • 58
    • 29
    • 22
    • 20
    • 18
    • 18
    • 17
    • 16
    • 16
    • 16
    • 12
    • 10
    • 10
    • 10
    • 10
    • 10
    • 10
    • 10
    • 10
    • 10
    • 8
    • 8
    • 5
    • 4
    • 4
    • 4
    • 4
    • 4
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser EGFR Antikörper ist unkonjugiert
    Applikation
    • 538
    • 254
    • 152
    • 151
    • 129
    • 102
    • 98
    • 93
    • 82
    • 48
    • 37
    • 34
    • 34
    • 19
    • 11
    • 8
    • 6
    • 5
    • 4
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunoprecipitation (IP)
    Spezifität
    This MAb reacts with a cytoplasmic domain of EGFR. EGFR is a type I receptor tyrosine kinase with sequence homology to erbB-1, -2, -3 -4 or HER-1, -2, -3 -4. It binds to Epidermal Growth Factor (EGF), Transforming Growth Factor-a (TGF-a), Heparin-binding EGF (HB-EGF), amphiregulin, betacellulin epiregulin.
    Keine Kreuzreaktivität
    Maus, Ratte (Rattus)
    Kreuzreaktivität (Details)
    Human. Does not react with Mouse or Rat.
    Aufreinigung
    1.0mg/ml of Ab purified from Bioreactor by Protein A/G.
    Immunogen
    Purified EGFR from A431 cells.
    Klon
    H9B4
    Isotyp
    IgG1 kappa
    Top Product
    Discover our top product EGFR Primärantikörper
  • Applikationshinweise

    Known_Application: Immunoprecipitation (1-2 μg/500 μg protein lysate), Western Blot (1-2 μg/mL for 2 hours at RT), Optimal dilution for a specific application should be determined.

    Positive_Control: A431 cells, Breast or Bladder cancer.

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Konzentration
    1.0 mg/mL
    Buffer
    Prepared in 10 mM PBS, WITHOUT BSA and Azide.
    Konservierungsmittel
    Azide free
    Lagerung
    -20 °C,-80 °C
    Informationen zur Lagerung
    Antibody without azide store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.
    Haltbarkeit
    24 months
  • Target
    EGFR (Epidermal Growth Factor Receptor (EGFR))
    Andere Bezeichnung
    EGFR (EGFR Produkte)
    Hintergrund
    Erbb1, ERBB1, Errp, HER1, mENA, PIG61, Proto-oncogene c-ErbB-1, Receptor Tyrosine Protein Kinase, ErbB1, Urogastrone, wa2, Wa5,EGFR (Epidermal Growth Factor Receptor)
    Cellular localisation: Cell surface
    Molekulargewicht
    ~170kDa (wild type) and ~145kDa (vIII variant)
    Gen-ID
    1956, 488293
    UniProt
    P00533
    Pathways
    NF-kappaB Signalweg, RTK Signalweg, Fc-epsilon Rezeptor Signalübertragung, EGFR Signaling Pathway, Neurotrophin Signalübertragung, Stem Cell Maintenance, Hepatitis C, Positive Regulation of Response to DNA Damage Stimulus, Interaction of EGFR with phospholipase C-gamma, Thromboxane A2 Receptor Signaling, EGFR Downregulation, S100 Proteine
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