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EGF Antikörper (AA 31-53)

Name: EGF Antikörper (AA 31-53)
SKU: ABIN676613
Price: 384.62 EUR
Availability: InStock

EGF Reaktivität: Human ELISA, IHC (p), IF (cc), IF (p), FACS, IHC (fro) Wirt: Kaninchen Polyclonal unconjugated

Formalin-fixed and paraffin embedded human lung carcinoma labeled with Anti-EGF(human) Polyclonal Antibody, Unconjugated (ABIN676613) at 1:200, followed by conjugation to the secondary antibody and DAB staining (EGF Antikörper (AA 31-53))

IHC

1 image

(1 reference)

Produktnummer ABIN676613

Datenblatt (PDF)

Target Alle EGF Antikörper anzeigen

EGF (Epidermal Growth Factor (EGF))
Bindungsspezifität
44

16

10

8

7

7

7

7

6

6

6

5

5

4

4

4

4

3

3

3

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1
AA 31-53
Reaktivität
144

85

50

12

11

5

4

1

1

1
Human
Wirt
209

30

9

3

1

1
Kaninchen
Passende Sekundärantikörper
Klonalität
214

38
Polyklonal
Konjugat
113

36

19

14

7

7

5

5

5

5

5

5

4

4

4

4

4

2

1

1

1

1

1
Dieser EGF Antikörper ist unkonjugiert
Applikation
200

86

62

52

52

28

24

24

17

16

14

14

8

8

4

4

3

2

2

1

1
ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Flow Cytometry (FACS), Immunohistochemistry (Frozen Sections) (IHC (fro))

Kreuzreaktivität

Human

Aufreinigung

Purified by Protein A.

Immunogen

KLH conjugated synthetic peptide derived from human EGF

Isotyp

IgG

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Applikationshinweise

ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Beschränkungen

Nur für Forschungszwecke einsetzbar
Format

Liquid

Konzentration

1 μg/μL

Buffer

0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Konservierungsmittel

ProClin

Vorsichtsmaßnahmen

This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung

4 °C,-20 °C

Informationen zur Lagerung

Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Haltbarkeit

12 months
da Rocha, Bastos, Domingues, Bento, Konietzko, da Cruz E Silva, Vieira: "APP Binds to the EGFR Ligands HB-EGF and EGF, Acting Synergistically with EGF to Promote ERK Signaling and Neuritogenesis." in: Molecular neurobiology, Vol. 58, Issue 2, pp. 668-688, (2021) (PubMed).
Target

EGF (Epidermal Growth Factor (EGF))

Andere Bezeichnung

EGF (EGF Produkte)

Synonyme

HOMG4 antikoerper, URG antikoerper, AI790464 antikoerper, CEGF antikoerper, epidermal growth factor antikoerper, pro-epidermal growth factor antikoerper, EGF antikoerper, egf antikoerper, CpipJ_CPIJ020278 antikoerper, Egf antikoerper

Hintergrund

Synonyms: URG, HOMG4, Pro-epidermal growth factor, EGF
Background: EGF stimulates the growth of various epidermal and epithelial tissues in vivo and in vitro and of some fibroblasts in cell culture. Magnesiotropic hormone that stimulates magnesium reabsorption in the renal distal convoluted tubule via engagement of EGFR and activation of the magnesium channel TRPM6. Can induce neurite outgrowth in motoneurons of the pond snail Lymnaea stagnalis in vitro (PubMed:10964941).

Gen-ID

1950

UniProt

P01133

Pathways

NF-kappaB Signalweg, RTK Signalweg, Fc-epsilon Rezeptor Signalübertragung, EGFR Signaling Pathway, Neurotrophin Signalübertragung, Regulation of Carbohydrate Metabolic Process, Hepatitis C, Protein targeting to Nucleus, Interaction of EGFR with phospholipase C-gamma, Thromboxane A2 Receptor Signaling, EGFR Downregulation