Arrestin 3 Antikörper (AA 251-418)

Produktnummer ABIN675069

Dieses Anti-Arrestin 3-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von Arrestin 3 in WB, ELISA, IHC (p), IF (cc), IF (p) und IHC (fro). Geeignet für Human, Maus und Ratte. Dieses Primary Antibody wurde in 1 Publikation zitiert.

Kurzübersicht für Arrestin 3 Antikörper (AA 251-418) (ABIN675069)

Target: Arrestin 3 (ARRB2) (Arrestin, beta 2 (ARRB2))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Arrestin 3 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Produktdetails anti-Arrestin 3 Antikörper

Bindungsspezifität: AA 251-418

Kreuzreaktivität: Human, Maus, Ratte

Homologie: Dog,Cow,Pig,Horse,Chicken,Rabbit,Guinea Pig

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human Beta-arrestin 2

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Haltbarkeit: 12 months

Referenzen für anti-Arrestin 3 Antikörper (ABIN675069)

Fan, Liao, Tang, Chen, Zhang, Liu, Zhong: "Role of ?2-adrenoceptor-?-arrestin2-nuclear factor-?B signal transduction pathway and intervention effects of oxymatrine in ulcerative colitis." in: Chinese journal of integrative medicine, Vol. 18, Issue 7, pp. 514-21, (2012) (PubMed).

Details zu Arrestin 3

Target: Arrestin 3 (ARRB2) (Arrestin, beta 2 (ARRB2))

Andere Bezeichnung: Beta arrestin 2

Hintergrund:

Synonyms: Beta-arrestin 2, Beta Arrestin 2, ARB 2, ARB2, ARR 2, ARR2, ARRB 2, ARRB2, ARRB2_HUMAN, Arrestin 3, Arrestin beta 2, Arrestin beta-2, BARR2, DKFZp686L0365, HGNC:712, Beta-arrestin-2.

Background: Members of arrestin/beta arrestin protein family are thought to participate in agonist mediated desensitization of G protein coupled receptors and cause specific dampening of cellular responses to stimuli such as hormones, neurotransmitters, or sensory signals. Arrestin beta 2, like arrestin beta 1, was shown to inhibit beta adrenergic receptor function in vitro. It is expressed at high levels in the central nervous system and may play a role in the regulation of synaptic receptors

Molekulargewicht: 45kDa

Gen-ID: 409

Pathways: Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling, cAMP Metabolic Process, Myometrial Relaxation and Contraction, Regulation of Leukocyte Mediated Immunity, Synaptic Membrane, Regulation of G-Protein Coupled Receptor Protein Signaling, CXCR4-mediated Signaling Events, Phototransduction, Thromboxane A2 Receptor Signaling