RAD21 Antikörper (AA 373-422)

Produktnummer ABIN6746464

Der Kaninchen Polyklonal Anti-RAD21-Antikörper wurde für WB validiert. Er ist geeignet, RAD21 in Proben von Human, Maus, Ratte, Rind (Kuh), Kaninchen, Hund, Pferd, Affe, Meerschweinchen, Huhn, Fledermaus, Schwein und Xenopus laevis zu detektieren. Es sind 2+ Publikationen verfügbar.

Kurzübersicht für RAD21 Antikörper (AA 373-422) (ABIN6746464)

Target: RAD21 (RAD21 Homolog (RAD21))

Reaktivität: Human, Maus, Ratte, Rind (Kuh), Kaninchen, Hund, Pferd, Affe, Meerschweinchen, Huhn, Fledermaus, Schwein, Xenopus laevis

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser RAD21 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-RAD21 Antikörper

Bindungsspezifität: AA 373-422

Spezifität: Rat RAD21

Homologie: Percent identity by BLAST analysis: Human, Mouse, Rat, Dog, Bovine, Rabbit, Horse, Guinea pig, Chicken, Xenopus (100%).

Aufreinigung: Immunoaffinity purified

Immunogen: Synthetic peptide located between aa373-422 of rat Rad21 (Q4KLH7, NP_001020872). Percent identity by BLAST analysis: Human, Chimpanzee, Gorilla, Orangutan, Gibbon, Monkey, Galago, Marmoset, Mouse, Rat, Elephant, Panda, Dog, Bovine, Bat, Rabbit, Horse, Pig, Opossum, Guinea pig, Turkey, Zebra finch, Chicken, Platypus, Lizard, Xenopus (100%), Salmon, Medaka, Zebrafish (92%).

Type of Immunogen: Synthetic peptide

Anwendungsinformationen

Applikationshinweise: Approved: WB (1 μg/mL)

Usage: Western Blot: Suggested dilution at 1 μg/mL in 5 % skim milk / PBS buffer, and HRP conjugated anti-Rabbit IgG should be diluted in 1: 50,000 - 100,000 as secondary antibody.

Kommentare:

Target Species of Antibody: Rat

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Distilled water

Konzentration: Lot specific

Buffer: Lyophilized from PBS with 2 % sucrose

Handhabung: Avoid repeat freeze-thaw cycles.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Long term: -20°C, the use of 50% glycerol is recommended if storing aliquots in -20°C for long term use (up to 1 year)
Short term (less than 1 week): 4°C. Avoid freeze-thaw cycles.

Referenzen für anti-RAD21 Antikörper (ABIN6746464)

Jia, Patwari, Srinivasula, Newland, Fernandes-Alnemri, Alnemri, Kelsey: "Bax translocation is crucial for the sensitivity of leukaemic cells to etoposide-induced apoptosis." in: Oncogene, Vol. 20, Issue 35, pp. 4817-26, (2001) (PubMed).

Hatai, Matsuzawa, Inoshita, Mochida, Kuroda, Sakamaki, Kuida, Yonehara, Ichijo, Takeda: "Execution of apoptosis signal-regulating kinase 1 (ASK1)-induced apoptosis by the mitochondria-dependent caspase activation." in: The Journal of biological chemistry, Vol. 275, Issue 34, pp. 26576-81, (2000) (PubMed).

Details zu RAD21

Target: RAD21 (RAD21 Homolog (RAD21))

Andere Bezeichnung: RAD21

Hintergrund: Name/Gene ID: RAD21

Synonyms: RAD21, CDLS4, HR21, KIAA0078, HHR21, NXP-1, NXP1, RAD21 (S. pombe) homolog, MCD1, Nuclear matrix protein 1, RAD21 homolog (S. pombe), HRAD21, SCC1, SCC1 homolog

Gen-ID: 5885

NCBI Accession: NP_001020872

UniProt: O60216

Pathways: Positive Regulation of Endopeptidase Activity