ERK1 Antikörper (pThr202, pThr204) (Biotin)

Produktnummer ABIN6735479

Dieses Maus Monoklonal-Antikörper erkennt spezifisch ERK1 in WB, ELISA, IP und ICC. Er zeigt eine Reaktivität gegenüber Human.

Kurzübersicht für ERK1 Antikörper (pThr202, pThr204) (Biotin) (ABIN6735479)

Target: ERK1 (MAPK3) (Mitogen-Activated Protein Kinase 3 (MAPK3))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser ERK1 Antikörper ist konjugiert mit Biotin

Applikation: Western Blotting (WB), ELISA, Immunoprecipitation (IP), Immunocytochemistry (ICC)

Produktdetails anti-ERK1 Antikörper (Biotin)

Bindungsspezifität: pThr202, pThr204

Spezifität: Recognizes the FLpTEpYVA motif of activated human ERK1 and ERK2. Requires phosphorylation both at the threonine and the tyrosine site and does not cross-react with the non-phosphorylated form of the protein. Does not cross-react with activated JNK or p38. Species cross-reactivity: mouse, rat, and canine.

Kreuzreaktivität: Hund, Maus, Ratte (Rattus)

Aufreinigung: Gel Filtration Chromatography

Immunogen: Synthetic peptide corresponding to the FLpTEpYVA motif of phosphorylated ERK1/2 (MAPK2/3). Conjugated to KLH.

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: ELISA (0.05 µg/mL), ICC (1 - 10 µg/mL), IP, WB (0.5 µg/mL)

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS, 0.09% sodium azide, G, sucrose, 40% glycerol.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeat freeze-thaw cycles.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Long term: -20°C, Short term: +4°C, Avoid freeze-thaw cycles.

Details zu ERK1

Target: ERK1 (MAPK3) (Mitogen-Activated Protein Kinase 3 (MAPK3))

Andere Bezeichnung: MAPK3 / ERK1

Hintergrund: Standard Gene Symbol: MAPK3, Gene Family: Protein Kinase, Gene Subfamily: MAPK, Synonyms: MAPK3, ERK-1, ERT2, HUMKER1A, HS44KDAP, MAP kinase 1, MAP kinase isoform p44, MAPK 1, MAPK 3, p44, p44MAPK, p44-MAPK, p44ERK1, Insulin-stimulated MAP2 kinase, MAP kinase 3, p44-ERK1, ERK1, PRKM3

Gen-ID: 5595

UniProt: P27361

Pathways: MAPK Signalweg, RTK Signalweg, Interferon-gamma Pathway, Fc-epsilon Rezeptor Signalübertragung, Neurotrophin Signalübertragung, Response to Growth Hormone Stimulus, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Hepatitis C, Protein targeting to Nucleus, Toll-Like Receptors Cascades, Signaling Events mediated by VEGFR1 and VEGFR2, Signaling of Hepatocyte Growth Factor Receptor, VEGFR1 Specific Signals, S100 Proteine