TLR5 Antikörper (AA 701-810)

Produktnummer ABIN673239

Dieses Anti-TLR5-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von TLR5 in WB, ELISA und IHC (p). Geeignet für Human und Maus. Dieses Primary Antibody wurde in 4+ Publikationen zitiert.

Kurzübersicht für TLR5 Antikörper (AA 701-810) (ABIN673239)

Target: TLR5 (Toll-Like Receptor 5 (TLR5))

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser TLR5 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Produktdetails anti-TLR5 Antikörper

Bindungsspezifität: AA 701-810

Kreuzreaktivität: Human, Maus

Homologie: Rat

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from mouse TLR5

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Haltbarkeit: 12 months

Referenzen für anti-TLR5 Antikörper (ABIN673239)

Li, Yu, Li, Liu, Jiao, Song, Lv, Qin: "Phycocyanin attenuates pulmonary fibrosis via the TLR2-MyD88-NF-κB signaling pathway." in: Scientific reports, Vol. 7, Issue 1, pp. 5843, (2017) (PubMed).

Sun, Zhan, Liang, Zhang, Song, Han, Hou: "In vivo Toll-like receptor 5 (TLR5) imaging with radiolabeled anti-TLR5 monoclonal antibody in rapamycin-treated mouse allogeneic skin transplantation model." in: Transplant infectious disease : an official journal of the Transplantation Society, Vol. 17, Issue 1, pp. 80-8, (2015) (PubMed).

Hao, Zhang, Liang, Song, Hou: "rFliC prolongs allograft survival in association with the activation of recipient Tregs in a TLR5-dependent manner." in: Cellular & molecular immunology, Vol. 11, Issue 2, pp. 206-14, (2014) (PubMed).

Sun, Yang, Liang, Zhang, Song, Han, Hou: "Non-invasive imaging of allogeneic transplanted skin graft by (131) I-anti-TLR5 mAb." in: Journal of cellular and molecular medicine, (2014) (PubMed).

Details zu TLR5

Target: TLR5 (Toll-Like Receptor 5 (TLR5))

Andere Bezeichnung: TLR5

Hintergrund:

Synonyms: Toll-like receptor 5, Tlr5

Background: Participates in the innate immune response to microbial agents. Mediates detection of bacterial flagellins. Acts via MYD88 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response (By similarity).

Gen-ID: 53791

UniProt: Q9JLF7

Pathways: TLR Signalweg, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Toll-Like Receptors Cascades