ERCC3 Antikörper (AA 665-715)

Produktnummer ABIN6719310

Produktdetails anti-ERCC3 Antikörper

Target: ERCC3 (DNA Repair Protein Complementing XP-B Cells (ERCC3))

Bindungsspezifität: AA 665-715

Reaktivität: Human, Ratte, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ERCC3 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Verwendungszweck: Rabbit IgG polyclonal antibody for XPB detection. Tested with WB, Direct ELISA in Human,Mouse,Rat.

Kreuzreaktivität (Details): No cross reactivity with other proteins.

Produktmerkmale: Rabbit IgG polyclonal antibody for XPB detection. Tested with WB, Direct ELISA in Human,Mouse,Rat.

Aufreinigung: Immunogen affinity purified.

Immunogen: E. coli-derived human XPB recombinant protein (Position: Q665-K715).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise:

Application details: Western blot|0.1-0.5 μg/mL Direct ELISA|0.1-0.5 μg/mL

Kommentare:

Tested Species: In-house tested species with positive results. Other applications have not been tested. Optimal dilutions should be determined by end users.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.

Details zu ERCC3

Target: ERCC3 (DNA Repair Protein Complementing XP-B Cells (ERCC3))

Andere Bezeichnung: ERCC3 (ERCC3 Produkte)

Synonyme: BTF2 antikoerper, GTF2H antikoerper, RAD25 antikoerper, TFIIH antikoerper, XPB antikoerper, BTF2 p89 antikoerper, Ercc-3 antikoerper, wu:fc25f08 antikoerper, ERCC excision repair 3, TFIIH core complex helicase subunit antikoerper, excision repair cross-complementing rodent repair deficiency, complementation group 3 antikoerper, excision repair cross-complementation group 3 antikoerper, ERCC3 antikoerper, Ercc3 antikoerper, ercc3 antikoerper

Hintergrund:

Synonyms: General transcription and DNA repair factor IIH helicase subunit XPB, TFIIH subunit XPB, Basic transcription factor 2 89 kDa subunit, BTF2 p89, DNA excision repair protein ERCC-3, DNA repair protein complementing XP-B cells, TFIIH basal transcription factor complex 89 kDa subunit, TFIIH 89 kDa subunit, TFIIH p89, Xeroderma pigmentosum group B-complementing protein, ERCC3, XPB, XPBC

Background: XPB (xeroderma pigmentosum type B) is an ATP-dependent DNA helicase in humans that is a part of the TFIIH transcription factor complex. This gene encodes an ATP-dependent DNA helicase that functions in nucleotide excision repair. The encoded protein is a subunit of basal transcription factor 2 (TFIIH) and, therefore, also functions in class II transcription. Mutations in this gene are associated with Xeroderma pigmentosum B, Cockayne's syndrome, and trichothiodystrophy. Alternative splicing results in multiple transcript variants.

Gen-ID: 2071

UniProt: P19447

Pathways: DNA Reparatur