Growth Hormone Receptor Antikörper (AA 101-200)

Produktnummer ABIN671481

Dieses Anti-Growth Hormone Receptor-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von Growth Hormone Receptor in WB, ELISA, FACS, IF (cc), IF (p), IHC (p) und IHC (fro). Geeignet für Human, Maus, Ratte, Schwein und Schaf. Dieses Primary Antibody wurde in 7+ Publikationen zitiert.

Kurzübersicht für Growth Hormone Receptor Antikörper (AA 101-200) (ABIN671481)

Target: Growth Hormone Receptor (GHR)

Reaktivität: Human, Maus, Ratte, Schwein, Schaf

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Growth Hormone Receptor Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Flow Cytometry (FACS), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Produktdetails anti-Growth Hormone Receptor Antikörper

Bindungsspezifität: AA 101-200

Kreuzreaktivität: Human, Maus, Schwein, Ratte, Schaf

Homologie: Dog,Cow,Chicken

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human GHR

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:300-5000
ELISA 1:500-1000
FCM 1:20-100
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Haltbarkeit: 12 months

Referenzen für anti-Growth Hormone Receptor Antikörper (ABIN671481)

Zhou, Yang, Yang, Huang, Zhou, Jiang, Yang: "Effects of zearalenone on the localization and expression of the growth hormone receptor gene in the uteri of post-weaning piglets." in: Asian-Australasian journal of animal sciences, Vol. 31, Issue 1, pp. 32-39, (2018) (PubMed).

Zhao, Feng, Zhang, Kou, Li, Liu, Zhang, Cui, Chu, Shen, Min: "Inhibition of peripubertal sheep mammary gland development by cysteamine through reducing progesterone and growth factor production." in: Theriogenology, Vol. 89, pp. 280-288, (2017) (PubMed).

Chu, Zhao, Feng, Zhang, Liu, Cheng, Li, Shen, Cao, Li, Min: "MicroRNA-126 participates in lipid metabolism in mammary epithelial cells." in: Molecular and cellular endocrinology, Vol. 454, pp. 77-86, (2017) (PubMed).

Hetz, Menzies, Shaw, Rao, Clarke, Renfree: "Growth axis maturation is linked to nutrition, growth and developmental rate." in: Molecular and cellular endocrinology, Vol. 411, pp. 38-48, (2015) (PubMed).

Song, Yang, Tang, Chen: "Effects of sericin on the testicular growth hormone/insulin-like growth factor-1 axis in a rat model of type 2 diabetes." in: International journal of clinical and experimental medicine, Vol. 8, Issue 7, pp. 10411-9, (2015) (PubMed).

Yang, Sun, Sun, Qi: "Effect of suppressor of cytokine signaling 2 (SOCS2) on fat metabolism induced by growth hormone (GH) in porcine primary adipocyte." in: Molecular biology reports, Vol. 39, Issue 9, pp. 9113-22, (2012) (PubMed).

Wang, Zhou, Lin, Wang, Lin, Li: "RhGH attenuates ischemia injury of intrahepatic bile ducts relating to liver transplantation." in: The Journal of surgical research, Vol. 171, Issue 1, pp. 300-10, (2011) (PubMed).

Details zu Growth Hormone Receptor

Target: Growth Hormone Receptor (GHR)

Andere Bezeichnung: GHR

Hintergrund:

Synonyms: GHBP, Growth hormone receptor, GH receptor, Somatotropin receptor, GHR

Background: Receptor for pituitary gland growth hormone involved in regulating postnatal body growth. On ligand binding, couples to the JAK2/STAT5 pathway (By similarity). The soluble form (GHBP) acts as a reservoir of growth hormone in plasma and may be a modulator/inhibitor of GH signaling. Isoform 2 up-regulates the production of GHBP and acts as a negative inhibitor of GH signaling.

Gen-ID: 2690

UniProt: P10912

Pathways: NF-kappaB Signalweg, JAK-STAT Signalweg, Response to Growth Hormone Stimulus