CDK1 Antikörper (pTyr15)

Produktnummer ABIN6658147

Hersteller Produkt- Nr.: 600-401-160

Der Kaninchen Polyklonal anti-CDK1 Antikörper wird verwendet zum Nachweis von CDK1 in Proben von Ratte. Er wurde validiert für WB und ELISA.

Kurzübersicht für CDK1 Antikörper (pTyr15) (ABIN6658147)

Target: CDK1 (Cyclin-Dependent Kinase 1 (CDK1))

Reaktivität: Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CDK1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Produktdetails anti-CDK1 Antikörper

Bindungsspezifität: pTyr15

Hersteller Produkt- Nr.: 600-401-160

Hersteller: Rockland

Verwendungszweck: cdc2 phospho Y15 Antibody

Kreuzreaktivität (Details): Anti-cdc2 pY15 Antibody is directed against rat cdc2 protein phosphorylated at Y15.

Aufreinigung: The antibody was prepared from monospecific antiserum by immunoaffinity chromatography using phospho peptide coupled to agarose beads followed by solid phase adsorption(s) against non-phospho peptide and non-specific peptide to remove any unwanted reactivities.

Immunogen: Anti-cdc2 pY15 Antibody was produced by repeated immunizations with a synthetic peptide corresponding to amino acid residues surrounding Tyr 15.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise:

ELISA_Dilution: 1:10,000

Western_Blot_Dilution: 1:1000

Kommentare:

Anti-cdc2 pY15 antibody is tested for use in ELISA and Western Blotting. Specific conditions for reactivity should be optimized by the end user. Expect a band of approximately 34 kDa in size corresponding to cdc2 protein in the appropriate cell lysate or extract.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer:

Buffer: 0.01 M HEPES, 0.15 M Sodium Chloride, pH 7.5

Stabilizer: 0.1 mg/mL Bovine Serum Albumin (BSA) - IgG and Protease free, 50 % (v/v) Glycerol

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store vial at -20° C prior to opening.  This product is stable at 4° C as an undiluted liquid.  For extended storage, aliquot contents and freeze at -20° C or below.  Avoid cycles of freezing and thawing. Dilute only prior to immediate use.

Haltbarkeit: 12 months

Details zu CDK1

Target: CDK1 (Cyclin-Dependent Kinase 1 (CDK1))

Andere Bezeichnung: cdc2

Hintergrund:

Synonyms: CDC-like kinase 2, Clk2

Background: Cdc2 pY15 antibody recognizes Cdc2 which is a highly conserved protein serine kinase that plays a key role in regulation of the cell cycle. The ability of cdc2 to exercise control over the cell cycle is dependent upon the phosphorylation of Tyr15 in cdc2. Cdc2 expression in brain has been linked to both neurogenesis and apoptosis. Anti-Cdc2 pY15 antibody is ideal for investigators involved in Cell Signaling, Neuroscience, Signal Transduction research.

Gene Name: CLK2

Gen-ID: 54237

NCBI Accession: NP_062169

UniProt: P39951

Pathways: Zellzyklus, Fc-epsilon Rezeptor Signalübertragung, Neurotrophin Signalübertragung, Activation of Innate immune Response, Mitotic G1-G1/S Phases, DNA Replication, M Phase, Toll-Like Receptors Cascades, Synthesis of DNA