ELK1 Antikörper (pSer383)

Produktnummer ABIN6657457

Hersteller Produkt- Nr.: 600-401-d34

Der Kaninchen Polyklonal Anti-ELK1-Antikörper wurde für WB und ELISA validiert. Er ist geeignet, ELK1 in Proben von Human zu detektieren.

Kurzübersicht für ELK1 Antikörper (pSer383) (ABIN6657457)

Target: ELK1 (ELK1, Member of ETS Oncogene Family (ELK1))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ELK1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Produktdetails anti-ELK1 Antikörper

Bindungsspezifität: pSer383

Hersteller Produkt- Nr.: 600-401-d34

Hersteller: Rockland

Verwendungszweck: Elk-1 phospho S383 Antibody

Kreuzreaktivität (Details): Anti-Elk-1 pS383 antibody is directed against Elk-1.

Aufreinigung: Anti-Elk-1 pS383 antibody was prepared from monospecific antiserum by immunoaffinity chromatography using phospho peptide coupled to agarose beads followed by solid phase adsorption(s) against non-phospho peptide and non-specific peptide to remove any unwanted reactivities.

Immunogen: Anti-Elk-1 pS383 Antibody was produced in rabbit by repeated immunizations with synthetic phospho-peptide corresponding to amino acid residues surrounding Ser383 conjugated to KLH.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise:

ELISA_Dilution: 1:10000

Western_Blot_Dilution: 1:1000

Kommentare:

Anti-Elk-1 pS383 Antibody is tested for use in ELISA and Western Blotting. Specific conditions for reactivity should be optimized by the end user. Expect a band of approximately 46 kDa in size corresponding to Elk-1 phosphorylated at Ser383 in the appropriate cell lysate or extract.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer:

Buffer: 0.01 M HEPES, 0.15 M Sodium Chloride, pH 7.5

Stabilizer: 0.1 mg/mL Bovine Serum Albumin (BSA) - IgG and Protease free, 50 % (v/v) Glycerol

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store vial at -20° C prior to opening.  This product is stable at 4° C as an undiluted liquid.  For extended storage, aliquot contents and freeze at -20° C or below.  Avoid cycles of freezing and thawing. Dilute only prior to immediate use.

Haltbarkeit: 12 months

Details zu ELK1

Target: ELK1 (ELK1, Member of ETS Oncogene Family (ELK1))

Andere Bezeichnung: Elk-1

Hintergrund:

Synonyms: ETS domain-containing protein Elk-1

Background: Elk-1 Antibody detects Elk-1 which is a transcription factor involved in mediating gene transcription in response to growth factors. Elk-1 is thought to be phosphorylated by MAP kinase at Ser383 and phosphorylation at this site is essential for the transcriptional activity of Elk-1. Phosphorylation of Elk-1 has also been implicated in synaptic plasticity in the adult hippocampus. Anti-Elk-1 pS383 Antibody is ideal for investigators involved in Cell Signaling, Cell Motility and, Cancer Research.

Gene Name: ELK1

Gen-ID: 2002

UniProt: P19419

Pathways: MAPK Signalweg, Neurotrophin Signalübertragung, Activation of Innate immune Response, Toll-Like Receptors Cascades, Signaling of Hepatocyte Growth Factor Receptor, BCR Signaling