VEGFR2/CD309 Antikörper (Extracellular Domain)

Produktnummer ABIN6655552

Hersteller Produkt- Nr.: 200-301-p49

Der Maus Monoklonal anti-VEGFR2/CD309 Antikörper wird verwendet zum Nachweis von VEGFR2/CD309 in Proben von Human. Er wurde validiert für IHC.

Kurzübersicht für VEGFR2/CD309 Antikörper (Extracellular Domain) (ABIN6655552)

Target: VEGFR2/CD309 (VEGFR2) (VEGF Receptor 2 (VEGFR2))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser VEGFR2/CD309 Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (IHC)

Klon: KDR-1

Produktdetails anti-VEGFR2/CD309 Antikörper

Bindungsspezifität: Extracellular Domain

Hersteller Produkt- Nr.: 200-301-p49

Hersteller: Rockland

Verwendungszweck: VEGFR2 Antibody

Kreuzreaktivität (Details): This product reacts with human.

Aufreinigung: Anti-VEGFR2 antibody was purified from mouse ascites by protein A chromatography.

Immunogen: VEGFR2 antibody was produced in mice by repeated immunizations with recombinant protein corresponding to human extracellular domain of VEGFR-2 (KDR).

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: Optional[Neutralization_Dilution]: 1:100-1:500

Kommentare:

Anti-VEGFR2 is tested for Immunohistochemistry-F. Specific conditions for reactivity should be optimized by the end user. Expect a band approximately ~151.5 kDa corresponding to the appropriate cell lysate or extract.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution:

Reconstitution_Buffer: Neutral PBS

Reconstitution_Volume: 1.0 mL

Buffer:

Buffer: 1.2 % sodium acetate

Stabilizer: 2 mg BSA

Preservative: 0.01 % (w/v) Sodium Azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store vial at 4° C prior to opening. Aliquot contents and freeze at -20° C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4° C as an undiluted liquid. Dilute only prior to immediate use.

Haltbarkeit: 12 months

Details zu VEGFR2/CD309

Target: VEGFR2/CD309 (VEGFR2) (VEGF Receptor 2 (VEGFR2))

Andere Bezeichnung: VEGFR2

Hintergrund:

Synonyms: CD309, VEGFR, FLK1, VEGFR2, TYROSINE KINASE GROWTH FACTOR RECEPTOR, FLK1, MOUSE, HOMOLOG OF, VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR, VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR 2, Fetal liver kinase 1, Kinase insert domain receptor, Protein-tyrosine kinase receptor flk-1

Background: VEGF, a homodimeric glycoprotein of relative molecular mass 45,000, is the only mitogen that specifically acts on endothelial cells. The importance of VEGF and its receptor system in tumor growth and intervention in this system may provide promising approaches to cancer therapy. VEGF receptor 2 is a member of a receptor tyrosine kinase family.Like other growth factor receptors, upon ligand binding VEGF receptor 2 dimerises and is autophosphorylated on multiple tyrosine residues. This antibody is suitable for researchers interested in cell signaling and cancer research.

Gene Name: KDR

Gen-ID: 3791

NCBI Accession: NP_002244

UniProt: P35968

Pathways: RTK Signalweg, Glycosaminoglycan Metabolic Process, Signaling Events mediated by VEGFR1 and VEGFR2, Growth Factor Binding, Regulation of long-term Neuronal Synaptic Plasticity, VEGF Signaling