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VEGFR2/CD309 Antikörper (Tyr1175)

Name: VEGFR2/CD309 Antikörper (Tyr1175)
SKU: ABIN652371
Price: 445.5 EUR
Availability: InStock

VEGFR2 Reaktivität: Human, Maus WB, FACS Wirt: Kaninchen Polyclonal RB25842 unconjugated

Western blot analysis of KDR Antibody (ABIN652371 and ABIN2841771) in mouse lung tissue lysates (35 μg/lane). (VEGFR2/CD309 Antikörper (Tyr1175))

KDR Antibody (ABIN652371 and ABIN2841771) flow cytometric analysis of MDA-M cells (right histogram) compared to a negative control cell (left histogram). (VEGFR2/CD309 Antikörper (Tyr1175))

FACS

2 Abbildungen

Produktnummer ABIN652371

Datenblatt (PDF)

Target Alle VEGFR2/CD309 (VEGFR2) Antikörper anzeigen

VEGFR2/CD309 (VEGFR2) (VEGF Receptor 2 (VEGFR2))
Bindungsspezifität
37

36

27

22

20

16

16

14

13

10

10

8

7

6

6

6

5

5

5

4

4

3

3

3

3

3

2

2

2

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1
AA 1153-1182, Tyr1175
Reaktivität
305

204

145

18

9

7

4

3

3

3

2

1

1

1

1

1

1

1

1

1
Human, Maus
Wirt
301

54

18

2

1

1

1
Kaninchen
Passende Sekundärantikörper
Klonalität
297

81
Polyklonal
Konjugat
163

34

20

14

14

13

13

12

11

11

11

11

6

6

6

6

6

3

2

2

2

2

2

1

1

1

1

1

1

1

1
Dieser VEGFR2/CD309 Antikörper ist unkonjugiert
Applikation
232

131

96

86

59

34

26

24

23

14

13

12

9

7

7

4

3

2

2

2

2

1

1

1

1
Western Blotting (WB), Flow Cytometry (FACS)

Aufreinigung

This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen

This KDR antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1153-1182 amino acids from human KDR.

Klon

RB25842

Isotyp

Ig Fraction

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Applikationshinweise

WB: 1:1000. FC: 1:10~50

Beschränkungen

Nur für Forschungszwecke einsetzbar
Format

Liquid

Buffer

Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Konservierungsmittel

Sodium azide

Vorsichtsmaßnahmen

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung

4 °C,-20 °C

Informationen zur Lagerung

Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Haltbarkeit

6 months
Target

VEGFR2/CD309 (VEGFR2) (VEGF Receptor 2 (VEGFR2))

Andere Bezeichnung

KDR (VEGFR2 Produkte)

Synonyme

CD309 antikoerper, FLK1 antikoerper, VEGFR antikoerper, VEGFR2 antikoerper, 6130401C07 antikoerper, Flk-1 antikoerper, Flk1 antikoerper, Krd-1 antikoerper, Ly73 antikoerper, VEGFR-2 antikoerper, sVEGFR-2 antikoerper, Vegfr-2 antikoerper, FLK-1 antikoerper, flk-1 antikoerper, vegfr-2 antikoerper, KDR antikoerper, FLK/KDR antikoerper, flk1 antikoerper, flk1b antikoerper, kdrb antikoerper, si:busm1-205d10.1 antikoerper, si:ch211-254j6.1 antikoerper, si:ch211-278f21.4 antikoerper, wu:fc31a09 antikoerper, fk52c05 antikoerper, flk antikoerper, kdr antikoerper, kdra antikoerper, vegfr2 antikoerper, vegfr4 antikoerper, vegr2 antikoerper, wu:fk52c05 antikoerper, kinase insert domain receptor antikoerper, kinase insert domain protein receptor antikoerper, vascular endothelial growth factor receptor kdr-like antikoerper, kinase insert domain receptor (a type III receptor tyrosine kinase) antikoerper, kinase insert domain receptor like antikoerper, KDR antikoerper, Kdr antikoerper, LOC100136647 antikoerper, kdr antikoerper, kdrl antikoerper

Hintergrund

KDR is a major growth factor for endothelial cells. This protein encodes one of the two receptors of the KDR. This receptor, known as kinase insert domain receptor, is a type III receptor tyrosine kinase. It functions as the main mediator of VEGF-induced endothelial proliferation, survival, migration, tubular morphogenesis and sprouting. The signalling and trafficking of this receptor are regulated by multiple factors, including Rab GTPase, P2Y purine nucleotide receptor, integrin alphaVbeta3, T-cell protein tyrosine phosphatase, etc..

Molekulargewicht

151527

Gen-ID

3791

NCBI Accession

NP_002244

UniProt

P35968

Pathways

RTK Signalweg, Glycosaminoglycan Metabolic Process, Signaling Events mediated by VEGFR1 and VEGFR2, Growth Factor Binding, Regulation of long-term Neuronal Synaptic Plasticity, VEGF Signaling