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BCL3 Antikörper (C-Term)

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch BCL3 in WB, ELISA, IHC, IP, IF, FACS und FM. Er zeigt eine Reaktivität gegenüber Human.
Rockland
Produktnummer ABIN6655290
Hersteller Produkt- Nr.: 600-401-gu4

Kurzübersicht für BCL3 Antikörper (C-Term) (ABIN6655290)

Target

Alle BCL3 Antikörper anzeigen
BCL3 (B-Cell CLL/lymphoma 3 (BCL3))

Reaktivität

  • 38
  • 36
  • 6
Human

Wirt

  • 46
  • 8
  • 5
Kaninchen

Klonalität

  • 48
  • 11
Polyklonal

Konjugat

  • 31
  • 5
  • 4
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Dieser BCL3 Antikörper ist unkonjugiert

Applikation

  • 45
  • 18
  • 13
  • 13
  • 12
  • 10
  • 10
  • 8
  • 8
  • 6
  • 3
  • 3
  • 1
  • 1
  • 1
Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunoprecipitation (IP), Immunofluorescence (IF), Flow Cytometry (FACS), Fluorescence Microscopy (FM)
  • Bindungsspezifität

    • 15
    • 7
    • 5
    • 4
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term

    Hersteller Produkt- Nr.

    600-401-gu4

    Hersteller

    Rockland

    Verwendungszweck

    BCL3 Antibody

    Kreuzreaktivität (Details)

    This affinity purified antibody is directed against human BCL3.

    Aufreinigung

    This product was affinity purified from monospecific antiserum by immunoaffinity purification.

    Sterilität

    Sterile filtered

    Immunogen

    Anti-BCL3 antibody was prepared from whole rabbit serum produced by repeated immunizations with a synthetic peptide corresponding to a C-Term portion of human BCL3 conjugated to Keyhole Limpet Hemocyanin (KLH).

    Isotyp

    IgG
  • Applikationshinweise

    Immunoprecipitation_Dilution: User Optimized

    ELISA_Dilution: 5.0 μg/mL

    Immunohistochemistry_Dilution: 1:200

    Flow_Cytometry_Dilution: User Optimized

    IF_Microscopy_Dilution: 10 μg/mL

    Western_Blot_Dilution: 1:1000

    Kommentare

    Anti-BCL-3 Antibody has been tested in Western Blot, ELISA, and Immunofluorescence. Expect a band at 47.5 kDa in western blot using appropriate lysates. Positive control used recombinant BCL3 protein, HEK293T overexpressing BCL3 or U87 whole cell lysates at 1μg/mL in WB, and U87MG with PFA at 10μg/mL in IF. Although not tested, this antibody is likely functional in immunohistochemistry, flow cytometry, and immunoprecipitation.

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Liquid

    Buffer

    Buffer: 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2

    Stabilizer: None

    Preservative: 0.01 % (w/v) Sodium Azide

    Konservierungsmittel

    Sodium azide

    Vorsichtsmaßnahmen

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Lagerung

    4 °C,-20 °C

    Informationen zur Lagerung

    Store vial at -20° C prior to opening. Aliquot contents and freeze at -20° C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4° C as an undiluted liquid. Dilute only prior to immediate use.

    Haltbarkeit

    12 months
  • Target

    BCL3 (B-Cell CLL/lymphoma 3 (BCL3))

    Andere Bezeichnung

    BCL3

    Hintergrund

    Synonyms: rabbit anti-BCL3 antibody, rabbit anti-BCL-3 Antibody, BCL 3, B-cell lymphoma 3 protein, B-cell lymphoma 3 protein Antibody

    Background: BCL3 belongs to the ANKRD family. The protein contains seven ankyrin repeats, which are closely related to those found in I kappa B proteins. BCL3 functions as a transcriptional co-activator, regulator of transcriptional activation, promotor of transcription, and inhibitor of nuclear translocation of NF-kappa B. It is a proto-oncogene identified by its translocation into the immunoglobulin alpha-locus in some cases of B-cell leukemia. BCL3 contributes to the regulation of cell proliferation. Therefore, BCL3 may be associated with B-cell chronic lymphocytic leukemia, lymphoma, or other hematologic diseases. Anti-BCL3 Antibody is useful for researchers interested in Cancer Research, NF-Kappa B Pathway, and TNF Signaling Pathway.

    Gene Name: BCL3

    Gen-ID

    602

    NCBI Accession

    NP_005169

    UniProt

    P20749

    Pathways

    NF-kappaB Signalweg, Maintenance of Protein Location, Protein targeting to Nucleus
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