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MECP2 Antikörper (C-Term)

This anti-MECP2 antibody (ABIN6655271) is a Rabbit Polyclonal antibody detecting MECP2 in WB, ELISA, ChIP. Suitable for Human.
Rockland
Produktnummer ABIN6655271
Hersteller Produkt- Nr.: 600-401-x39

Quick Overview for MECP2 Antikörper (C-Term) (ABIN6655271)

Target

Alle MECP2 Antikörper anzeigen
MECP2 (Methyl CpG Binding Protein 2 (MECP2))

Reaktivität

  • 110
  • 42
  • 31
  • 6
  • 6
  • 5
  • 4
  • 4
  • 4
  • 3
  • 3
  • 1
  • 1
  • 1
Human

Wirt

  • 102
  • 19
  • 1
Kaninchen

Klonalität

  • 103
  • 19
Polyklonal

Konjugat

  • 81
  • 9
  • 7
  • 7
  • 6
  • 6
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Dieser MECP2 Antikörper ist unkonjugiert

Applikation

  • 92
  • 61
  • 48
  • 26
  • 20
  • 16
  • 11
  • 10
  • 6
  • 3
  • 1
  • 1
  • 1
Western Blotting (WB), ELISA, Chromatin Immunoprecipitation (ChIP)
  • Bindungsspezifität

    • 14
    • 11
    • 10
    • 8
    • 7
    • 7
    • 7
    • 4
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term

    Hersteller Produkt- Nr.

    600-401-x39

    Hersteller

    Rockland

    Verwendungszweck

    MeCP2 Antibody

    Kreuzreaktivität (Details)

    This product reacts with human MeCP2.

    Aufreinigung

    Anti-MeCP2 Antibody was purified by affinity purification.

    Sterilität

    Sterile filtered

    Immunogen

    Anti-MeCP2 Antibody was produced in rabbits by repeated immunizations with a synthetic peptide containing the C-terminal region of human MeCP2.

    Isotyp

    IgG
  • Applikationshinweise

    ChIP_Dilution: 5 μg per IP

    ELISA_Dilution: 1:1,000

    Western_Blot_Dilution: 1:1,000

    Kommentare

    Anti-MeCP2 Antibody is tested for Chromatin Immunoprecipitation, ELISA and Western Blots. Specific conditions for reactivity should be optimized by the end user. Expect a band approximately 70 kDa in the appropriate cell lysate or extract.

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Liquid

    Buffer

    Buffer: 0.01 M Sodium Phosphate, 0.25 M Sodium Chloride, pH 7.2

    Stabilizer: None

    Preservative: 0.05 % (w/v) Sodium Azide and 0.05 % ProClin 300

    Konservierungsmittel

    ProClin, Sodium azide

    Vorsichtsmaßnahmen

    This product contains Sodium azide and ProClin: POISONOUS AND HAZARDOUS SUBSTANCES which should be handled by trained staff only.

    Lagerung

    4 °C,-20 °C

    Informationen zur Lagerung

    Store vial at -20° C prior to opening. Aliquot contents and freeze at -20° C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4° C as an undiluted liquid. Dilute only prior to immediate use.

    Haltbarkeit

    12 months
  • Target

    MECP2 (Methyl CpG Binding Protein 2 (MECP2))

    Andere Bezeichnung

    MeCP2

    Hintergrund

    Synonyms: Methyl-CpG-binding protein 2, MeCP-2 protein, AUTSX3, MRX16, MRX79, MRXS13, MRXSL, PPMX, RTS, RTT

    Background: MeCP2 is a chromosomal protein with abundant binding sites in the chromatin. It belongs to the family of methyl CpG binding proteins which also comprises MBD1, MBD2, MBD3 and MBD4. MeCP2 can bind specifically to methylated promoters, thereby repressing transcription. This transcriptional repression is mediated through interaction with histone deacetylase and the corepressor SIN3A. MeCP2 also is essential for development. Mutations in MeCP2 are the cause of several types of mental retardation including Rett syndrome, a progressive neurological disorder that causes mental retardation in females and mental retardation syndromic X-linked type 13, and may also be involved in Angelman syndrome and susceptibility to some types of autism. Anti-MeCP2 Antibody is ideal for research in Epigenetics, Embryonic Development and Neuroscience.

    Gene Name: MECP2

    Gen-ID

    4204

    NCBI Accession

    NP_001104262

    UniProt

    P51608

    Pathways

    Inositol Metabolic Process, Chromatin Binding, Synaptic Membrane
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