RGS14 Antikörper (Regulator of G-Protein Signaling 14)

Details for Product anti-RGS14 Antibody No. ABIN6572098
Antigen
  • RPIP1
  • MGC80558
  • RGS14
  • rgs14
  • wu:fi04g12
  • regulator of G protein signaling 14
  • regulator of G-protein signaling 14
  • regulator of G-protein signaling 14 L homeolog
  • regulator of G-protein signalling 14
  • regulator of G protein signaling 14a
  • RGS14
  • Rgs14
  • rgs14.L
  • rgs14
  • rgs14a
Reaktivität
Human, Maus
81
31
21
3
3
3
3
2
2
2
1
1
1
Wirt
Kaninchen
69
7
7
1
Klonalität
Polyklonal
Konjugat
Dieser RGS14 Antikörper ist unkonjugiert
5
4
3
3
3
3
1
1
1
1
1
1
Applikation
Western Blotting (WB)
73
43
10
9
4
2
2
1
1
1
1
1
Optionen
Immunogen Recombinant protein of human RGS14
Isotyp IgG
Reinigung Affinity purification
Plasmids, Primers & others Plasmide, Primers & weitere RGS14 products on genomics-online (e.g. as negative or positive controls)
Antigen
Andere Bezeichnung RGS14 (RGS14 Antibody Abstract)
Hintergrund

Synonyms: Highly similar to rap1/rap2 interacting protein,OTTHUMP00000223586,OTTHUMP00000223587,Regulation of G protein signaling 14,Regulator of G protein signaling 14,Regulator of G protein signalling 14,Regulator of G-protein signaling 14,RGS 14,RGS14,RGS14

Background: This gene encodes a member of the regulator of G-protein signaling family. This protein contains one RGS domain, two Raf-like Ras-binding domains (RBDs), and one GoLoco domain. The protein attenuates the signaling activity of G-proteins by binding, through its GoLoco domain, to specific types of activated, GTP-bound G alpha subunits. Acting as a GTPase activating protein (GAP), the protein increases the rate of conversion of the GTP to GDP. This hydrolysis allows the G alpha subunits to bind G beta/gamma subunit heterodimers, forming inactive G-protein heterotrimers, thereby terminating the signal. Alternate transcriptional splice variants of this gene have been observed but have not been thoroughly characterized.

Molekulargewicht

Observed_MW: 54kDa

Calculated_MW: 21kDa/36kDa/44kDa/61kDa

Gen-ID 10636
UniProt O43566
Pathways Myometrial Relaxation and Contraction, Regulation of G-Protein Coupled Receptor Protein Signaling, Platelet-derived growth Factor Receptor Signaling
Applikations-hinweise WB 1:500 - 1:2000
Beschränkungen Nur für Forschungszwecke einsetzbar
Konzentration 1 mg/mL
Buffer Buffer: PBS with 0.02 % sodium azide, 50 % glycerol,  pH 7.3.
Konservierungs-mittel Sodium azide
Vorsichtsmaßnahmen This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung -20 °C
Informationen zur Lagerung Store at -20°C. Avoid freeze / thaw cycles.
Bilder des Herstellers
Image no. 1 for anti-Regulator of G-Protein Signaling 14 (RGS14) antibody (ABIN6572098) Western blot analysis of extracts of various cell lines, using RGS14 antibody.
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