PHLPP1 Antikörper (PH Domain and Leucine Rich Repeat Protein Phosphatase 1)

Details for Product anti-PHLPP1 Antibody No. ABIN6571995
Antigen
  • PHLPP
  • PLEKHE1
  • SCOP
  • AI836256
  • Phlpp
  • Plekhe1
  • mKIAA0606
  • Scop
  • PH domain and leucine rich repeat protein phosphatase 1
  • PHLPP1
  • phlpp1
  • Phlpp1
Reaktivität
Human, Maus, Ratte (Rattus)
49
25
22
Wirt
Kaninchen
50
Klonalität
Polyklonal
Konjugat
Dieser PHLPP1 Antikörper ist unkonjugiert
2
2
2
2
2
2
2
Applikation
Western Blotting (WB)
35
15
8
3
3
2
2
2
1
1
Optionen
Immunogen Recombinant protein of human PHLPP1
Isotyp IgG
Reinigung Affinity purification
Plasmids, Primers & others Plasmide, Primers & weitere PHLPP1 products on genomics-online (e.g. as negative or positive controls)
Antigen
Andere Bezeichnung PHLPP1 (PHLPP1 Antibody Abstract)
Hintergrund

Synonyms: hSCOP,KIAA0606,PH domain and leucine rich repeat protein phosphatase,PH domain leucine rich repeat containing protein phosphatase,PH domain leucine rich repeat protein phosphatase,PH domain leucine-rich repeat-containing protein phosphatase 1,PH domain-containing family E member 1,PHLP1,PHLPP,Phlpp1,Pleckstrin homology domain containing family E (with leucine rich repeats) member 1,Pleckstrin homology domain containing family E protein 1,Pleckstrin homology domain-containing family E member 1,PLEKHE 1 protein,PLEKHE1,SCN circadian oscillatory protein,SCOP,Suprachiasmatic nucleus circadian oscillatory protein,Suprachiasmatic nucleus circadian protein

Background: This gene encodes a member of the serine/threonine phosphatase family. The encoded protein promotes apoptosis by dephosphorylating and inactivating the serine/threonine kinase Akt, and functions as a tumor suppressor in multiple types of cancer. Increased expression of this gene may also play a role in obesity and type 2 diabetes by interfering with Akt-mediated insulin signaling.

Molekulargewicht

Observed_MW: 185kDa

Calculated_MW: 133kDa/184kDa

Gen-ID 23239
UniProt O60346
Pathways PI3K-Akt Signalweg, Fc-epsilon Rezeptor Signalübertragung, Neurotrophin Signalübertragung
Applikations-hinweise WB 1:500 - 1:2000
Beschränkungen Nur für Forschungszwecke einsetzbar
Konzentration 1 mg/mL
Buffer Buffer: PBS with 0.02 % sodium azide, 50 % glycerol,  pH 7.3.
Konservierungs-mittel Sodium azide
Vorsichtsmaßnahmen This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung -20 °C
Informationen zur Lagerung Store at -20°C. Avoid freeze / thaw cycles.
Bilder des Herstellers
Image no. 1 for anti-PH Domain and Leucine Rich Repeat Protein Phosphatase 1 (PHLPP1) antibody (ABIN6571995) Western blot analysis of extracts of various cell lines, using PHLPP1 antibody.
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