PHLPP1 Antikörper
Kurzübersicht für PHLPP1 Antikörper (ABIN6571995)
Target
Alle PHLPP1 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Aufreinigung
- Affinity purification
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Immunogen
- Recombinant fusion protein of human PHLPP1 (NP_919431.2).
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Isotyp
- IgG
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Applikationshinweise
- IF 1:50-1:200
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- 1 mg/mL
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Buffer
- PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- Store at -20°C. Avoid freeze / thaw cycles.
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- PHLPP1 (PH Domain and Leucine Rich Repeat Protein Phosphatase 1 (PHLPP1))
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Andere Bezeichnung
- PHLPP1
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Hintergrund
- This gene encodes a member of the serine/threonine phosphatase family. The encoded protein promotes apoptosis by dephosphorylating and inactivating the serine/threonine kinase Akt, and functions as a tumor suppressor in multiple types of cancer. Increased expression of this gene may also play a role in obesity and type 2 diabetes by interfering with Akt-mediated insulin signaling.
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Molekulargewicht
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Observed_MW: 185kDa
Calculated_MW: 133kDa/184kDa
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Gen-ID
- 23239
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UniProt
- O60346
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Pathways
- PI3K-Akt Signalweg, Fc-epsilon Rezeptor Signalübertragung, Neurotrophin Signalübertragung
Target
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