Phospholipase C beta 1 Antikörper (phospholipase C, beta 1 (phosphoinositide-Specific))

Details for Product anti-PLCB1 Antibody No. ABIN6569015
Target
Reaktivität
Human, Maus, Ratte
37
27
26
4
3
3
3
2
1
1
1
1
Wirt
Kaninchen
35
2
1
Klonalität
Polyklonal
Konjugat
Dieser Phospholipase C beta 1 Antikörper ist unkonjugiert
3
2
2
2
1
1
1
1
1
1
1
1
1
1
Applikation
Immunofluorescence (IF), Immunohistochemistry (IHC), Western Blotting (WB)
21
13
8
6
6
3
1
1
1
1
1
1
Optionen
Immunogen Recombinant protein of human PLCB1
Isotyp IgG
Reinigung Affinity purification
Target
Andere Bezeichnung PLCB1 (PLCB1 Antibody Abstract)
Hintergrund

Synonyms: 1 phosphatidylinositol 4,5 bisphosphate phosphodiesterase beta 1,1-phosphatidyl-D-myo-inositol-4,5-bisphosphate,1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-1,EIEE12,Inositoltrisphosphohydrolase,Monophosphatidylinositol phosphodiesterase,Phosphb,Phosphoinositidase C,Phosphoinositide phospholipase C,Phosphoinositide phospholipase C-beta 1,Phosphoinositide phospholipase C-beta-1,Phospholipase C beta 1 (phosphoinositide-specific),Phospholipase C I,Phospholipase C-beta-1,Phospholipase C-I,PI PLC,PLC 1,PLC beta 1,PLC I,PLC-154,PLC-beta-1,PLC-I,PLC154,Plcb,Plcb1,Plcb1 protein ,PLCB1,PLCbeta1,Triphosphoinositide phosphodiesterase

Background: The protein encoded by this gene catalyzes the formation of inositol 1,4,5-trisphosphate and diacylglycerol from phosphatidylinositol 4,5-bisphosphate. This reaction uses calcium as a cofactor and plays an important role in the intracellular transduction of many extracellular signals. This gene is activated by two G-protein alpha subunits, alpha-q and alpha-11. Two transcript variants encoding different isoforms have been found for this gene.

Molekulargewicht

Observed_MW: 145kDa

Calculated_MW: 133kDa/138kDa

Gen-ID 23236
UniProt Q9NQ66
Pathways WNT Signalweg, AMPK Signaling, Thyroid Hormone Synthesis, Inositol Metabolic Process, Regulation of Muscle Cell Differentiation, Regulation of G-Protein Coupled Receptor Protein Signaling, Proton Transport, Skeletal Muscle Fiber Development, CXCR4-mediated Signaling Events, G-protein mediated Events
Applikations-hinweise WB 1:500 - 1:2000 IHC 1:50 - 1:200 IF 1:50 - 1:200
Beschränkungen Nur für Forschungszwecke einsetzbar
Konzentration 1 mg/mL
Buffer Buffer: PBS with 0.02 % sodium azide, 50 % glycerol,  pH 7.3.
Konservierungs-mittel Sodium azide
Vorsichtsmaßnahmen This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung -20 °C
Informationen zur Lagerung Store at -20°C. Avoid freeze / thaw cycles.
Bilder
Image no. 1 for anti-phospholipase C, beta 1 (phosphoinositide-Specific) (PLCB1) antibody (ABIN6569015) Immunohistochemistry of paraffin-embedded human kidney cancer using PLCB1 antibody.
Image no. 2 for anti-phospholipase C, beta 1 (phosphoinositide-Specific) (PLCB1) antibody (ABIN6569015) Immunohistochemistry of paraffin-embedded rat brain using PLCB1 antibody.
Image no. 3 for anti-phospholipase C, beta 1 (phosphoinositide-Specific) (PLCB1) antibody (ABIN6569015) Immunofluorescence analysis of U2OS cells using PLCB1 antibody.
Image no. 4 for anti-phospholipase C, beta 1 (phosphoinositide-Specific) (PLCB1) antibody (ABIN6569015) Western blot analysis of extracts of NCI-H460 cells, using PLCB1 antibody.